OA-2000测量的长眼轴白内障患者眼球生物学参数分析  

Analysis of ocular biological parameters in cataract patients with long axial lengths measured by OA-2000

作　　者：刁莉莉 杨文利[1] 姚宁[1] 张丛[1] Diao Lili;Yang Wenli;Yao Ning;Zhang Cong(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology and Visual Science,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院、北京同仁眼科中心、眼科学与视觉科学北京市重点实验室,100730

出　　处：《眼科》2023年第2期103-107,共5页Ophthalmology in China

摘　　要：目的分析长眼轴白内障患者眼球生物学参数特点。设计回顾性病例系列。研究对象2021年6月至2022年4月在北京同仁医院眼科就诊的白内障患者1000例(1000眼)。方法采用OA-2000测量眼轴长度(AL),根据测得AL将患者分为正常眼轴对照组(22 mm≤AL<26 mm)和长眼轴组(AL≥26 mm),长眼轴组根据眼轴长度进一步分为4组:A组(26 mm≤AL<28 mm)187眼;B组(28 mm≤AL<30 mm)140眼;C组(30 mm≤AL<32 mm)130眼;D组(AL≥32 mm)93眼。对正常眼轴及长眼轴组眼、长眼轴各亚组的眼球生物学参数进行比较,并分析眼轴长度与眼球生物学参数、年龄与眼球生物学参数之间的相关性。主要指标AL、角膜曲率(Kf、Ks、Km)、前房深度(ACD)、晶状体厚度(LT)、角膜横径(WTW)。结果长眼轴组患者Kf、Ks、Km、角膜散光、ACD、LT、WTW分别为(43.07±1.61)D、(44.65±1.71)D、(43.91±1.62)D、(1.52±0.77)D、(3.28±0.47)mm、(4.55±0.41)mm、(11.52±0.45)mm,正常眼轴组患者Kf、Ks、Km、角膜散光、ACD、LT、WTW分别为(44.51±1.42)D、(45.47±1.52)D、(44.98±1.51)D、(0.92±0.66)D、(3.01±0.41)mm、(4.63±0.46)mm、(11.40±0.48)mm,两组比较差异均有统计学意义(P均<0.05);长眼轴组4个不同眼轴长度亚组Kf、Ks、Km、角膜散光、ACD、LT、WTW比较差异均有统计学意义(P均<0.05)。应用Pearson相关分析,长眼轴组AL与LT、WTW呈正相关,相关系数分别为(r=0.249,P<0.0001)、(r=0.182,P=0.002),与Kf、Ks、Km、ACD呈负相关(r=-0.219,P<0.0001)、(r=-0.183,P<0.0001)、(r=-0.194,P<0.0001)、(r=-0.328,P<0.0001);年龄与Kf、Ks、Km、WTW之间均无相关性(P均>0.05),与LT呈正相关(r=0.299,P<0.0001),与AL、ACD呈负相关(r=-0.245,P<0.0001)、(r=-0.228,P<0.0001)。结论与正常眼轴组患者相比,长眼轴组患者Kf、Ks、Km较小,ACD较深、LT较薄、WTW较长;长眼轴组患者AL与LT、WTW呈正相关,与Kf、Ks、Km、ACD呈负相关,年龄与LT呈正相关,与AL、ACD呈负相关。Objective To analyze the characteristics of ocular biological parameters of cataract patients with long axial lengths(AL).Design Retrospective cases series.Participants From June 2021 to April 2022,1000 cataract patients(1000 eyes)who received medical treatment in Beijing Tongren Eye Center.Methods On basis of the axial length measured by OA-2000,the patients were divided into normal control group(22 mm≤AL<26 mm)and long axial group(AL≥26 mm).And the long axial group was further divided into 4 groups according to the axial length,namely,Group A(26 mm≤AL<28 mm)187 cases(187 eyes),Group B(28 mm≤AL<30 mm)140 cases(140 eyes),Group C(30 mm≤AL<32 mm)130 cases,(130 eyes),Group D(AL≥32 mm)93 cases(93 eyes).The ocular biological parameters were compared between eyes with normal axial and long axial group and each subgroup in the long axial group,and the correlation between axial length and ocular biological parameters,age and ocular biological parameters were analyzed.Main Outcome Measures AL,keratometry(Kf,Ks,Km),anterior chamber depth(ACD),lens thickness(LT),white to white(WTW).Results The Kf,Ks,Km,corneal astigmatism,ACD,LT,and WTW of patients in the long axial group was(43.07±1.61)D,(44.65±1.71)D,(43.91±1.62)D,(1.52±0.77)D,(3.28±0.47)mm,(4.55±0.41)mm,(11.52±0.45)mm,respectively.Which was(44.51±1.42)D,(45.47±1.52)D,(44.98±1.51)D,(0.92±0.66)D,(3.01±0.41)mm,(4.63±0.46)mm,(11.40±0.48)mm,respectively in the normal control group(all P<0.05).There were statistically significant differences in Kf,Ks,Km,corneal astigmatism,ACD,LT and WTW among the four sub groups in the long axial group with different axial lengths(all P<0.05).Through Pearson correlation analysis,in the long axial group,AL was positively correlated with LT and WTW(r=0.249,P<0.0001)and(r=0.182,P=0.002)respectively;it was negatively correlated with Kf,Ks,Km,ACD(r=-0.219,P<0.0001),(r=-0.183,P<0.0001),(r=-0.194,P<0.0001),(r=-0.328,P<0.0001)respectively.There was no correlation between age and Kf,Ks,Km,WTW(all P>0.05);it was positively cor

关 键 词：生物测量 眼轴 角膜曲率 前房深度 晶状体厚度 角膜横径 

分 类 号：R776.1[医药卫生—眼科]