无创呼吸机治疗在阻塞性睡眠呼吸暂停低通气综合征患者围手术期的临床效果观察  

Clinical Effect of Non-Invasive Ventilator in the Perioperative Period of Patients with Obstructive Sleep Apnea Hypopnea Syndrome

作　　者：叶孟好 YE Meng-hao(Department of Otolaryngology,Zhongshan Hospital,Xiamen University,Fujian Xiamen 361004)

机构地区：[1]厦门大学附属中山医院耳鼻咽喉头颈外科,福建厦门361004

出　　处：《中国医疗器械信息》2023年第3期125-127,共3页China Medical Device Information

摘　　要：目的:分析无创呼吸机治疗阻塞性睡眠呼吸暂停低通气综合征(Obstructive Sleep Apnea Hypopnea Syndrome,OSAHS)患者效果。方法:选择2020年5月~2021年5月86例OSAHS患者进行研究,采用随机数表法分为观察组(43例)与对照组(43例)。对照组患者予以常规治疗,观察组患者在此基础上结合无创呼吸机治疗。对比临床疗效、睡眠质量、动脉血气水平、炎性因子水平、术后出血率。结果:(1)临床疗效对比:观察组患者临床疗效显著高于对照组,有统计学意义(P<0.05);(2)睡眠质量对比:观察组患者各项睡眠治疗评分显著低于对照组,有统计学意义(P<0.05);(3)动脉血气水平对比:两组患者pH值差异较小,无统计学意义(P>0.05),观察组患者PCO_(2)、TCO_(2)水平显著低于对照组,PO_(2)水平显著高于对照组,有统计学意义(P<0.05);(4)炎性因子水平对比:观察组患者CRP、ESR水平显著低于对照组,有统计学意义(P<0.05);(5)术后出血率对比:观察组术后出血率显著低于对照组,有统计学意义(P<0.05)。结论:无创呼吸机对OSAHS患者具有显著疗效,可有效改善患者睡眠质量,提高患者动脉血氧分压,降低患者炎性因子水平,降低术后出血。Objective:To analyze the effect of non-invasive ventilator on patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:86 OSAHS patients from May 2020 to May 2021 were selected for the study,and they were divided into observation group(43 cases)and control group(43 cases)by random number table method.Patients in the control group received conventional treatment,and patients in the observation group were treated with noninvasive ventilator on this basis.Compare the clinical efficacy,sleep quality,arterial blood gas level,inflammatory factor level,postoperative bleeding.Results:①Comparison of clinical efficacy:the clinical efficacy of the observation group was significantly higher than that of the control group(P<0.05),which was statistically significant;②Comparison of sleep quality:the sleep treatment scores of the observation group were significantly lower than those of the control group,(P<0.05),statistically significant;③Comparison of arterial blood gas levels:the difference in pH between the two groups was small,(P>0.05),which was not statistically significant,and the PCO_(2) and TCO_(2) levels of the observation group were significantly lower In the control group,the PO_(2) level was significantly higher than that of the control group(P<0.05),which was statistically significant;④Comparison of inflammatory factor levels:CRP and ESR levels in the observation group were significantly lower than those in the control group(P<0.05),statistically significant;⑤Comparison of postoperative blood loss:postoperative bleeding in the observation group was significantly lower than that of the control group(P<0.05),which was statistically significant.Conclusion:The non-invasive ventilator has a significant effect on patients with OSAHS.It can effectively improve the sleep quality of patients,increase the arterial blood oxygen pressure,reduce the level of inflammatory factors,and reduce postoperative bleeding.

关 键 词：无创呼吸机 阻塞性睡眠呼吸暂停低通气综合症 炎性因子 

分 类 号：R781.4[医药卫生—口腔医学]