胎儿脐膨出孕期管理及娩出后转运1例并文献复习  

Pregnant management of fetal omphalocele and transport after delivery:a case report and literature review

作　　者：胡凌云[1] 卢彦平[1] 王旖[1] 游艳琴[1] Hu Lingyun;Lu Yanping;Wang Yi;You Yanqin(Department of Obstetrics,the First Medical Center of PLA General Hospital,Beijing 100048,China)

机构地区：[1]解放军总医院第一医学中心产科,北京100048

出　　处：《中国医药》2023年第4期596-598,共3页China Medicine

基　　金：国家重点研发计划(2021YFC1005301)。

摘　　要：脐膨出是一种发生在脐带根部、大小不定的中线腹壁缺损,表面是由羊膜、华通胶和腹膜组成的囊膜,囊内含有疝出的腹腔内容物,该出生缺陷是最常见的胎儿腹壁缺损,我国胎儿中发生率约为3.38/10000。含有肝脏组织的脐膨出,最早可在妊娠9~10周通过经阴道超声做出产前诊断。脐膨出与染色体非整倍体具有较高的相关性,除染色体层面异常外,根据文献报道,还与遗传综合征相关。本文介绍1例我们收治的胎儿脐膨出病例的孕期管理及分娩后转运情况,并进行了相关文献复习。Omphalocele is a midline abdominal wall defect of variable size,which occurs at the root of the umbilical cord.The surface is a sac membrane composed of amnion,Wharton's jelly and peritoneum,and the sac contains herniated abdominal contents.This birth defect is the most common fetal abdominal wall defect,and the incidence rate in China is about 3.38/10000.Omphalocele,which contains the hepatic tissue,can be diagnosed antenatally by transvaginal ultrasound as early as 9-10 weeks of gestation.Omphalocele has a high correlation with chromosome aneuploid.In addition to chromosomal abnormalities,it is also associated with genetic syndromes according to literature reports.This article introduces the pregnant management and transport after delivery of a case of fetal omphalocele treated by us,and reviews the relevant literature.

关 键 词：脐膨出 染色体 微缺失微重复 产前咨询 产前诊断 

分 类 号：R656.3[医药卫生—外科学]