肿瘤内科住院患者机体组成及营养状况分析研究  

Body composition and nutritional status of inpatients in oncology department

作　　者：孟卫芬 岳静燕 臧婷 蒋华 张云妍 王梦洁 Meng Weifen;Yue Jingyan;Zang Ting;Jiang Hua;Zhang Yunyan;Wang Mengjie(Cancer Center,Changzhou Second People's Hospital Affiliated to Nanjing Medical University,Changzhou 213003,Jiangsu,China;Department of Nutrition,Changzhou Second People's Hospital Affiliated to Nanjing Medical University,Changzhou 213003,Jiangsu,China)

机构地区：[1]南京医科大学附属常州第二人民医院肿瘤中心,江苏常州213003 [2]南京医科大学附属常州第二人民医院营养科,江苏常州213003

出　　处：《肿瘤代谢与营养电子杂志》2023年第2期236-242,共7页Electronic Journal of Metabolism and Nutrition of Cancer

基　　金：吴阶平医学基金会(320.6750.19007);江苏省高校优势学科建设工程项目(NYZLKF-2-202106)。

摘　　要：目的调查肿瘤内科住院患者机体组成及营养状况,分析不同性别、不同年龄患者营养状况的差异及相关性,为尽早实施肿瘤患者的营养治疗提供依据。方法回顾性分析2020年7月至2021年4月在南京医科大学附属常州第二人民医院肿瘤中心应用临床营养检测分析仪进行营养诊疗的411例住院患者的营养状况评估及体成分测试数据,按照年龄分为非老年组(<65岁)162例(男性91例,女性71例)和老年组(≥65岁)249例(男性144例,女性105例),分析不同性别、不同年龄肿瘤患者机体组成成分、营养状况,以及相位角与营养风险筛查和营养评估的相关性。结果所有患者中,营养风险发生率为44.77%,中度营养不良发生率37.23%,重度营养不良发生率37.47%。男性患者中,与非老年组相比,老年组患者体重、肌肉量、总水分、骨骼肌指标显著性降低,差异有统计学意义[(64.88±10.26)kg比(59.42±10.75)kg;(49.1±6.86)kg比(44.95±5.93)kg;(38.32±5.27)kg比(35.15±4.58)kg;(28.64±4.56)kg比(25.84±3.91)kg,P<0.05],营养风险发生率显著增加(24.18%比56.25%,P<0.05),重度营养不良发生率显著增加(20.88%比46.53%,P<0.05)。女性患者中,与非老年组相比,老年组患者各项体成分指标均无显著性差异(P>0.05),仅重度营养不良发生率显著增加(32.39%比42.86%,P<0.05)。不同性别、不同年龄肿瘤患者中,相位角与营养风险和营养不良的发生显著负相关。结论肿瘤内科住院患者中,老年患者重度营养不良的发生率显著增加,且男性各项体成分指标下降明显,临床中应特别关注老年男性肿瘤患者营养不良的发生及体成分的检测。Objective To investigate the nutritional status and body composition of hospitalized cancer patients,analyze the diferences and correlations in nutritional status of inpatients in oncology department of different genders and different ages,and provide an evidence for the implementation of nutritional therapy for cancer patients.Method Retrospectively analyze the nutritional status and body composition of 411 inpatients who were in the oncology department Cancer Center Changzhou Second People's Hospital Affliated to Nanjing Medical University from July 2020 to April 2021 who applied the clinical nutrition analyzer for nutritional diagnosis and treatment.The patients were divided into non-elderly group(<65 years old)and elderly group(≥65 years old).The body composition,nutritional status of cancer patients of different genders and different ages,and the correlation between phase angle and nutritional risk screening and nutritional assessment were analyzed.Result The incidence of nutritional risk was 44.77%(NRS 2002≥3 points),the incidence of moderate malnutrition and severe malnutrition were 37.23%(PG-SGA was 4-8 points)and 37.47%(PG-SGA≥9 points)respectively among all patients.Among male patients,compared to non-elderly group,the body weight,muscle mass,total water content,and skeletal muscle indexes of the elderly group were significantly decreased,which was statistically significant[(64.88±10.26)kg vs(59.42±10.75)kg;(49.1±6.86)kg vs(44.95±5.93)kg;(38.32±5.27)kg vs(35.15±4.58)kg;(28.64±4.56)kg vs(25.84±3.91)kg,P<0.05],the incidence of nutritional risk and severe malnutrition increased significantly(24.18%vs 56.25%;20.88%vs 46.53%,P<0.05).Among female patients,compared to non-elderly group,there was no significant difference in body composition indexes of elderly patients(P>0.05),but the incidence of severe malnutrition increased significantly(32.39%vs 42.86%,P<0.05).Phase angle was negative correlated with nutritional risk and malnutrition in cancer patients of different sexes and ages,significantly

关 键 词：肿瘤 营养筛查 营养评估 体成分分析 相位角 

分 类 号：R73[医药卫生—肿瘤] R459.3[医药卫生—临床医学]