子宫动脉结扎或子宫动脉上行支结扎在子宫肌瘤剥除术中的应用及对术后降低瘤腔感染率的研究  

The application of ligation of uterine artery or ligation of ascending branch of uterine artery in hysteromyoma stripping and the study of reducing the rate of tumor cavity infection after operation

作　　者：郭娟 王浩[1] Guo Juan;Wang Hao(Department of Gynecology,The Third People's Hospital ofYancheng,Yancheng 224000,China)

机构地区：[1]盐城市第三人民医院妇科,江苏盐城224000

出　　处：《实用妇科内分泌电子杂志》2022年第34期34-36,40,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的分析子宫动脉结扎或子宫动脉上行支结扎在子宫肌瘤剥除术中的应用及对术后降低瘤腔感染率的影响。方法选取60例多发性子宫肌瘤患者,参照计算机分组法分为对照组与试验组,每组30例。对照组予以常规开腹或腹腔镜子宫肌瘤剥除术,试验组予以子宫动脉或其上行支结扎及肌瘤剥除术。比较两组手术效果。结果试验组术中出血量及术后引流量均少于对照组(P<0.05),两组手术时间、术后血肿时间比较,差异无统计学意义(P>0.05)。对照组患者术后瘤腔感染率为26.67%(8/30),试验组患者术后瘤腔感染率为6.67%(2/30),比较差异有统计学意义(P<0.05)。术前,两组C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-8(IL-8)及白细胞介素-6(IL-6)水平比较,差异无统计学意义(P>0.05);术后,两组CRP、TNF-α、IL-8及IL-6水平均较术前降低(P<0.05),但两组比较差异无统计学意义(P>0.05)。结论子宫动脉结扎或子宫动脉上行支结扎在子宫肌瘤剥除术中的应用能有效减少术中出血量及术后引流量,降低术后瘤腔感染率,促进患者术后康复。Objective To analyze the application of ligation of uterine artery or ligation of ascending branch of uterine artery in hysteromyomectomy and its effect on reducing the rate of tumor cavity infection after surgery.Methods 60 patients with multiple uterine fibroids were selected and divided into control group and experimental group according to computer grouping method,with 30 cases in each group.The control group was treated with conventional laparotomy or laparoscopic hysteromyomectomy,and the experimental group was treated with uterine artery or its ascending branch ligation and myomectomy.The results of operation were compared between the two groups.Results The intraoperative blood loss and postoperative drainage volume of experimental group were less than those of control group(P<0.05),and there was no statistical significance in the operation time and postoperative hematoma time between the two groups(P>0.05).The postoperative tumor cavity infection rate in control group was 26.67%(8/30),and that in experimental group was 6.67%(2/30),with statistical significance(P<0.05).Before surgery,there were no significant differences in the levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interleukin-8(IL-8)and interleukin-6(IL-6)between 2 groups(P>0.05).After surgery,the levels of CRP,TNF-α,IL-8 and IL-6 in 2 groups were decreased compared with those before surgery(P<0.05),but there was no statistical significance between 2 groups(P>0.05).Conclusion The application of ligation of uterine artery or the upper branch of uterine artery in hysteromyoma stripping can effectively reduce intraoperative blood loss and postoperative drainage volume,reduce postoperative tumor cavity infection rate,and promote postoperative rehabilitation of patients.

关 键 词：子宫肌瘤 子宫肌瘤剥除术 子宫动脉结扎 临床疗效 

分 类 号：R737.33[医药卫生—肿瘤]