口轮匝肌的肌电信号及起始阈电压值的研究  

Electromyographic signals and the starting threshold voltage of orbicularis oris muscle in healthy rhesus monkeys

作　　者：余爵波 张天振 许栋岳 李克勇 Yu Juebo;Zhang Tianzhen;Xu Dongyue;Li Keyong(Department of Otorhinolaryngology Head and Neck Surgery,Affiliated Hospital of Yangzhou University,Yangzhou 225001,China;Department of Otorhinolaryngology Head and Neck Surgery,Shanghai First People's Hospital,Shanghai 200080,China;Department of Otorhinolaryngology Head and Neck Surgery,Affiliated Hospital of Chifeng University,Chifeng 024050,China)

机构地区：[1]扬州大学附属医院耳鼻咽喉头颈外科,扬州225001 [2]上海市第一人民医院耳鼻咽喉科,上海200080 [3]内蒙古赤峰学院附属医院耳鼻咽喉头颈外科,赤峰024050

出　　处：《中华耳鼻咽喉头颈外科杂志》2023年第4期368-373,共6页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：国家自然科学基金(81070779);上海市科学技术委员会科研计划(14441902000)。

摘　　要：目的探讨健康恒河猴口轮匝肌(orbicularis oris muscle,OOM)不同运动模式下的肌电信号特征及产生收缩运动的起始阈电压值。方法于不同时间点应用肌电图与诱发电位仪,采集健康恒河猴OOM安静持续闭口状态时肌电幅值、自然闭口起始阈电压值及持续闭口状态下的起始阈电压值时的肌电信号,分析肌电信号的电压幅值变化情况,确立OOM收缩运动起始肌电信号的幅值区间。采用单因素方差分析法对数据进行统计学分析。结果定性分析结果示:健康猴OOM安静自然持续闭口状态的肌电图呈直线形,较平稳,绝对值波动在15~50μV之间;自然口唇收缩运动时肌电图的肌电波形迅速升高,其幅值波动较大,最高峰值绝对值可达数百微伏;而诱发持续闭口状态的肌电图其幅值高达数千微伏以上。定量分析结果示:在不同测试时间点下的健康恒河猴OOM安静自然持续闭口状态下的肌电幅值间比较,差异均无统计学意义(P值均>0.05);不同测试时间点下的健康恒河猴双侧OOM自然闭口运动状态时的阈电压值(平均值范围:57.17~57.47μV)和诱发持续闭口状态下引发OOM收缩的阈电压值(平均值范围:55.38~55.99μV)比较显示差异均无统计学意义(P值均>0.05)。安静自然持续闭口状态为(30.67±8.72)μV,自然闭口运动状态为(475.12±54.72)μV,诱发持续闭口状态为(921.22±312.79)μV,3种口唇运动模式下OOM肌电幅值绝对值的两两比较差异均有统计学意义(t值分别为-8.48、-9.35、-5.01,P值均<0.001)。结论OOM的肌电信号在不同运动模式下各具特点,可作为计算机判断识别此肌运动模式的依据,不同运动状态下的肌电阈电压值上限为55~60μV之间。Objective To investigate the characteristics of electromyography(EMG)signals and the starting threshold voltages of the orbicularis oris muscles(OOM)in healthy rhesus monkeys under different muscle movement conditions.Methods The EMG signals and the starting threshold voltages at different time points in 4 healthy rhesus monkeys were acquired and recorded with EMG device and evoked potentiometer.The voltage amplitude variation of EMG signals was analyzed,and the voltage amplitude range of EMG signals at the beginning of OOM contraction was established.The data were statistically analyzed by one-way ANOVA.Results The EMG of OOM in healthy monkeys in the quiet,natural and continuous mouth-closed state was linear and relatively stable,and the absolute value fluctuated between 15 and 50μV.The EMG waveform increased rapidly during the natural lip contraction movement,and its amplitude fluctuated greatly,with the highest absolute value of the peak value reaching hundreds of microvolts.The amplitude of EMG induced by continuous mouth closure was more than thousands of microvolts.There was no significant difference in EMG amplitudes of OOM in the healthy rhesus monkey under quiet and continuous lip closure at different time points(P>0.05).There was no significant difference in threshold voltages in the state of natural lip contraction of bilateral OOM at different time points(average range:57.17-57.47μV)in the healthy rhesus monkeys(P>0.05).There was no significant difference in threshold voltages of OOM induced by bilateral OOM at different time points(average range:55.38-55.99μV)in the healthy rhesus monkeys(P>0.05).There were significant differences in the absolute values of EMG amplitudes of OOM between the three lip movement modes:(30.67±8.72)μV in quiet and natural continuous lip closure(475.12±54.72)μV in natural lip contraction,and(921.22±312.79)μV in the induced persistent lip closure,with t values of-8.48,-9.35 and-5.01 respectively,all P<0.001.Conclusions The EMG signals of OOM show different characte

关 键 词：面神经麻痹 恒河猴 口轮匝肌 肌电信号 

分 类 号：R318[医药卫生—生物医学工程]