三重四极杆复合线性离子阱质谱联用技术在农兽药残留检测中的研究进展  

Research Progress of Triple Quadrupole-Linear Ion Trap Mass Spectrometry for Determination of Pesticides and Veterinary Drugs

作　　者：宣彤 祝军[2] 李巧莲 王岩松 袁帅 罗景阳 蒋笑妍 李娇 刘鑫 张承昕 Xuan Tong;Zhu Jun;Li Qiaolian;Wang Yansong;Yuan Shuai;Luo Jingyang;Jiang Xiaoyan;Li Jiao;Liu Xin;Zhang Chengxin(School of Public Health,Shenyang Medical College,Shenyang,110034;Shenyang Food and Drug Inspection Institute,Shenyang,110124;College of Food Science,Shenyang Agricultural University,Shenyang,110866)

机构地区：[1]沈阳医学院公共卫生学院,沈阳110034 [2]沈阳市食品药品检验所,沈阳110124 [3]沈阳农业大学食品学院,沈阳110866

出　　处：《化学通报》2023年第4期451-457,共7页Chemistry

基　　金：国家市场监督管理总局科技计划项目(2020MK134);辽宁省市场监督管理局科技计划项目(2022ZC023)资助。

摘　　要：三重四极杆复合线性离子阱质谱(QTRAP-MS/MS)联用技术可提供多种扫描模式,在保留良好选择性和灵敏度的同时提高仪器定性检测能力,在农兽药残留检测中具有独特优势。本文综合分析了近五年QTRAP-MS/MS在国内外农兽药残留检测中的应用现状,从QTRAP-MS/MS的结构及原理和检测前处理等方面展开概述,并对其未来发展趋势从前处理技术、微型便携化仪器、与其他仪器联用等方面进行展望,以期为食品安全、农药兽药残留检测提供参考。Triple quadrupole composite linear ion trap mass spectrometry(QTRAP-MS/MS)has special advantages in the detection of pesticide and veterinary drug residues because it can offer multiple scanning modes,enhance the instrument’s qualitative detection capacity while maintaining good selectivity and sensitivity.This article analyzed the status of pesticide and veterinary drug residues by QTRAP-MS/MS in the past five years,and gave an overview of structure and principle of QTRAP-MS/MS and common sample pre-treatment purification techniques for pesticide and veterinary drug residues.The prospect for improving the pre-treatment purification techniques,micro portable instruments and combination with other technologies was also discussed,in order to provide a reference for food safety and pesticide and veterinary drug residue detection.

关 键 词：三重四极杆线性离子阱质谱 农药残留 兽药残留 

分 类 号：O657.63[理学—分析化学] TS207.3[理学—化学]