典型蓝藻多肽的浓度水平、毒性及光化学行为的研究进展  

Research Progress in Concentration Levels,Toxicities and Phototransformations of Novel Cyanopeptides

作　　者：许雯 任鹏飞 张欣然 Xu Wen;Ren Pengfei;Zhang Xinran(School of Environmental Science and Engineering,Sun Yat-sen University,Guangzhou,510006;Guangzhou Municipal Engineering Design&Research Institute,Guangzhou,510060;Shenzhen Research Institute of Sun Yat-sen University,Shenzhen,518000)

机构地区：[1]中山大学环境科学与工程学院,广州510006 [2]广州市市政工程设计研究总院有限公司,广州510060 [3]中山大学深圳研究院,深圳518000

出　　处：《化学通报》2023年第4期458-464,450,共8页Chemistry

基　　金：深圳市科技计划项目(JCYJ20210324140812034)资助。

摘　　要：由于人为活动和气候变化,蓝藻水华污染已成为全球性环境问题。水华发生时藻类产生的毒性代谢物蓝藻多肽大量释放至水中,对生态系统和人类健康造成风险。本文系统梳理了包含微囊藻毒素在内的6种典型蓝藻多肽的浓度水平和毒性,并探讨了蓝藻多肽的光化学行为。结果显示,蓝藻多肽的浓度水平一般处于μg/L范围,其主要毒性位点为肝、肾和神经系统,致毒浓度LC_(50)在μmol/L范围。蓝藻多肽以间接光解为主,半衰期长短与蓝藻多肽本身的结构和所含的氨基酸基团种类以及环境水体pH大小等有关。本研究为解析蓝藻多肽的环境影响和环境归宿提供参考。Due to human activities and climate change,cyanobacterial bloom pollution has become a global environmental problem.Cyanopeptides,a kind of toxic metabolites,produced by algae during blooms,are released into water in large quantities,posing risks to ecosystems and human health.In this paper,the concentrations and toxicities of six typical cyanopeptides including microcystin are systematically reviewed,and the photochemical behaviors of cyanopeptides are also discussed.The results show that the concentrations of cyanopeptides are generally in the range ofμg·L^(-1),the main toxic sites are liver,kidney and nervous system,and the toxic concentration LC_(50) is in the range ofμmol·L^(-1).Indirect photodegradation is the main photodegradation pathway of cyanopeptides.The halflife of cyanopeptides is related to the structure and the types of amino acid groups of cyanopeptides,the pH value of environmental water and so on.This study provides a reference for the analysis of the environmental impact and environmental end-result of types of cyanopeptides.

关 键 词：蓝藻多肽 存在水平 毒性作用 光化学反应 

分 类 号：X171.5[环境科学与工程—环境科学]