心肌肌钙蛋白在急性缺血性脑卒中的研究进展  

Research progress of cardiac troponin in acute ischemic stroke

作　　者：陈凤 柏晓林 张力壬 王修哲 耿直[1] CHEN Feng;BAI Xiaolin;ZHANG Liren;WANG Xiuzhe;GENG Zhi(The Sixth People's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200233,China)

机构地区：[1]上海交通大学附属第六人民医院,上海200233

出　　处：《中国实用神经疾病杂志》2023年第4期498-502,共5页Chinese Journal of Practical Nervous Diseases

基　　金：转化医学国家重大科技基础设施(上海)开放课题(编号:TMSK-2020-122)。

摘　　要：心肌肌钙蛋白(cTn)是目前检测心肌损伤最敏感的生物标志物。近年来发现急性缺血性脑卒中群体常伴有c Tn升高的现象,且与脑卒中患者早期神经功能恶化、出血转化、认知功能受损及未来不良心血管事件密切相关。现就急性缺血性脑卒中背景下cTn升高的机制、应用价值、临床意义以及亟待解决的问题作一综述,以期为临床诊疗及cTn在缺血性脑卒中未来的应用提供参考。Cardiac troponin(cTn)is the most sensitive biomarker for detecting myocardial injury.In recent years,it has been found that increased cTn is often associated with acute ischemic stroke,and is closely related to early neurological deterioration,hemorrhage transformation,cognitive impairment and future adverse cardiovascular events in stroke patients.This article reviews the mechanism,application value,clinical significance and urgent problems of cTn elevation in the context of acute ischemic stroke,in order to provide reference for clinical and shed new light on the future application of cTn in ischemic stroke.

关 键 词：急性缺血性脑卒中 肌钙蛋白 心肌损伤 

分 类 号：R743.3[医药卫生—神经病学与精神病学]