基于RAPID软件的超时间窗前循环急性大血管闭塞性缺血性卒中患者Alberta卒中项目早期CT评分与核心梗死体积相关性分析  

Correlation analysis between Alberta stroke program early CT score based on RAPID software and core infarction volume in patients with anterior circulation acute ischemic stroke with large vessel occlusion over time window

作　　者：张龄文 刘莉[2] 廖娟 刘曙东 唐戈 陈宇 赵立波[1] 杨德雨[1] ZHANG Lingwen;LIU Li;LIAO Juan;LIU Shudong;TANG Ge;CHEN Yu;ZHAO Libo;YANG Deyu(Department of Neurology,Yongchuan Hospital of Chongqing Medical University,Chongqing402160,China;Department of Health Management,Yongchuan Hospital of Chongqing Medical University,Chongqing402160,China;Chongqing Key Laboratory of Cerebrovascular Disease Research,Chongqing402160,China)

机构地区：[1]重庆医科大学附属永川医院神经内科,重庆402160 [2]重庆医科大学附属永川医院健康管理科,重庆402160 [3]脑血管病研究重庆市重点实验室,重庆402160

出　　处：《中国医药导报》2023年第11期80-83,共4页China Medical Herald

基　　金：西藏自治区自然科学基金组团式援藏医学项目[XZ2020ZR-ZY68(Z)];重庆市科卫联合医学科研项目(2019 QNXM014)。

摘　　要：目的分析基于RAPID软件的超时间窗前循环急性大血管闭塞性缺血性卒中(AIS-LVO)患者Alberta卒中项目早期CT评分(ASPECTS)与核心梗死体积的相关性。方法选取2019年1月至2021年12月就诊于重庆医科大学附属永川医院的超时间窗前循环AIS-LVO患者98例,根据发病时间将其进一步分为发病时间明确患者(51例)和发病时间不明确患者(47例),收集其临床及影像资料,采用RAPID软件计算ASPECTS。运用Spearman相关系数分析ASPECTS与核心梗死体积的相关性,运用受试者操作特征(ROC)曲线分析ASPECTS对核心梗死体积≤70 ml的预测价值。结果ASPECTS与超时间窗前循环AIS-LVO患者及其中的发病时间明确患者的核心梗死体积均呈负相关(rs<0,P<0.05),与发病时间不明确患者无相关性(P>0.05)。ROC曲线结果显示,ASPECTS对超时间窗前循环AIS-LVO患者及其中的发病时间明确患者核心梗死体积≤70 ml均有预测价值(P<0.05),截断值均为7分。结论基于RAPID软件的超时间窗前循环AIS-LVO患者ASPECTS与其核心梗死体积具有相关性,有助于患者进一步治疗方案的判断。Objective To analyze the correlation between Alberta stroke program early CT score(ASPECTS)based on RAPID software and core infarction volume in patients with anterior circulation acute ischemic stroke with large vessel occlusion(AIS-LVO)over time window.Methods Ninety-eight patients with anterior circulation AIS-LVO over time window admitted to Yongchuan Hospital Affiliated to Chongqing Medical University from January 2019 to December 2021 were selected and further divided into patients with definite onset time(51 cases)and patients with unclear onset time(47 cases)according to the onset time.Clinical and imaging data of these patients were collected.ASPECTS was calculated by RAPID software.Spearman correlation coefficient was used to analyze the correlation between ASPECTS and core infarction volume,and receiver operating characteristic(ROC)curve was used to analyze the predictive value of ASPECTS for core infarction volume≤70 ml.Results There was a negative correlation between ASPECTS and core infarction volume in patients with anterior circulation AIS-LVO over time window and patients with definite onset time among them (rs<0, P<0.05), but no correlation with patients with unclear onset time (P>0.05). ROC curve results showed that ASPECTS had predictive value for core infarction volume ≤70 ml in patients with anterior circulation AIS-LVO over time window and patients with definite onset time among them (P<0.05), and cut-off values were seven points. Conclusion The ASPECTS based on RAPID software of patient with anterior circulation AIS-LVO over time window are correlated with their core infarct volume, which can help to determine the further treatment of patients.

关 键 词：大血管闭塞性脑梗死 Alberta卒中项目早期CT评分 核心梗死 相关性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]