检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:肖彩琴[1] XIAO Cai-qin(Chemical Engineering Institute,Jiuquan Vocational and Technical College,Jiuquan 735000,China)
机构地区:[1]酒泉职业技术学院化工学院,甘肃酒泉735000
出 处:《兰州石化职业技术学院学报》2022年第4期1-5,共5页Journal of Lanzhou Petrochemical Polytechnic
基 金:2020年甘肃省高等学校创新能力提升项目(2020B-379)。
摘 要:本文以邻硝基苯甲醛、对氨基苯乙酮为原料,设计了一种在无金属催化体系下合成(4-氨基苯)(苯并噻吩-2-基)甲酮的新方法,目标化合物结构经1H NMR,13 C NMR表征。对无金属催化环化反应进行反应条件探索,发现当羟醛缩合的产物丙烯酮与S 8以1∶5物料比混合,在DIPEA介导下,80℃,DMSO中反应16 h,可较高产率(68%)得到目标化合物。In this paper,a new method for the synthesis of(4-aminobenzene)(benzothiophen-2-yl)methanone with o-nitrobenzaldehyde and p-aminoacetophenone as raw materials was designed in a metal-free catalytic system.Its structure was characterized by 1 H NMR and 13 C NMR.The reaction conditions of metal-free catalytic cyclization were investigated.The reaction conditions of metal-free catalytic cyclization were investigated,and it was found that when the product of hydroxyl aldehyde condensation was mixed with elemental sulfur at a material ratio of 1∶5,and DIPEA was used as catalyst,the reaction in DMSO for 16 h at 80℃,the good yield(68%)of the target compound could be obtained.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.7