^(99)Tc^(m)-GSA和^(99)Tc^(m)-甲溴苯宁肝胆显像用于肝脏储备功能的评估及其进展  

Application and progress of ^(99)Tc^(m)--GSA and ^(99)Tc^(m)--mebrofenin hepatobiliary scintigraphy in liver reserve function assessment

作　　者：佟君羽 蔡海东[1] 马超 吕中伟[1] Tong Junyu;Cai Haidong;Ma Chao;Lyu Zhongwei(Department of Nuclear Medicine,Shanghai Tenth People′s Hospital,Tongji University School of Medicine,Shanghai 200072,China)

机构地区：[1]同济大学附属第十人民医院核医学科,上海200072

出　　处：《中华核医学与分子影像杂志》2023年第4期248-251,共4页Chinese Journal of Nuclear Medicine and Molecular Imaging

摘　　要：肝脏储备功能是指肝脏受损后机体维持肝脏机能的代偿能力,对肝恶性肿瘤病损切除术有重要的临床参考意义。核医学肝胆功能显像技术可以定量评估肝脏血流灌注,在肝脏储备功能的评估、术后并发症的预测方面具有一定的优势。^(99)Tc^(m)-半乳糖人血清白蛋白(GSA)和^(99)Tc^(m)-甲溴苯宁(mebrofenin)是评估肝脏储备功能常用的显像剂,该文就其在肝脏储备功能评估的应用及进展进行综述。The liver reserve function refers to the compensatory ability to maintain liver function after damage,providing implication for the resection of hepatic malignant tumor.Hepatobiliary scintigraphy imaging can provide quantitative evaluation of liver blood perfusion,and has advantages on the evaluation of liver reserve function and the prediction of postoperative complications.^(99)Tc^(m)--galactosyl serum albumin(GSA)and ^(99)Tc^(m)--mebrofenin are commonly used imaging agents for hepatobiliary scintigraphy imaging assessment of liver reserve function.This article reviews the application and progress of hepatobiliary scintigraphy in liver reserve function assessment.

关 键 词：肝功能试验 99m锝聚集白蛋白 苯胺化合物 放射性核素显像 发展趋势 

分 类 号：R575[医药卫生—消化系统]