生物合成氧化锌纳米颗粒材料及其抗菌应用  

Biosynthesis of zinc oxide nanoparticles and its application to antibacterial

作　　者：司银芳 胡语婕 张凡 董浩[2,3,5] 佘跃惠 SI Yinfang;HU Yujie;ZHANG Fan;DONG Hao;SHE Yuehui(College of Petroleum Engineering,Yangtze University,Wuhan 430100,Hubei,China;Hubei Cooperative Innovation Center of Unconventional Oil and Gas,Wuhan 430100,Hubei,China;Key Laboratory of Drilling and Production Engineering for Oil and Gas,Hubei Province,Wuhan 430100,Hubei,China;College of Energy,China University of Geosciences(Beijing),Beijing 100083,China;College of Chemistry&Environmental Engineering,Yangtze University,Jingzhou 434023,Hubei,China)

机构地区：[1]长江大学石油工程学院,湖北武汉430100 [2]非常规油气湖北省协同创新中心,湖北武汉430100 [3]湖北省钻采工程重点实验室,湖北武汉430100 [4]中国地质大学(北京)能源学院,北京100083 [5]长江大学化学与环境工程学院,湖北荆州434023

出　　处：《化工进展》2023年第4期2013-2023,共11页Chemical Industry and Engineering Progress

基　　金：国家自然科学基金重点项目(NSFC51634008);国家自然科学基金(NSFC51574038)。

摘　　要：随着环境污染加剧与抗生素的广泛使用,各种威胁人类健康的疾病逐渐爆发,病原菌对抗生素的耐药性问题也愈发严重。这促使许多研究都集中在对绿色环保、抗菌活性强、不易产生耐药性的新型抗菌剂的探索上,并且纳米技术已被证明可作为对抗病原菌的有效手段。氧化锌纳米颗粒材料具有优异的抗菌抑菌性能,有望作为新型金属离子抗菌材料而被广泛应用。与传统物理化学方法相比,氧化锌纳米颗粒的生物方法具有操作简单、安全性高、对环境污染小等优势,已成为纳米合成技术发展的新趋势。本文首先综述了利用植物、藻类、微生物等提取物进行氧化锌纳米颗粒的生物合成方法与合成机理,总结了氧化锌纳米颗粒的抗菌机制,讨论了氧化锌纳米材料在医药行业、纺织工业、食品行业、农业等相关领域的抗菌应用,最后进一步展望了含有氧化锌的创新型多金属复合型纳米颗粒的相关研究与应用前景,为氧化锌纳米技术发展提供了新思路。With the aggravation of environmental pollution and the widespread use of antibiotics,various diseases threatening human health have gradually broken out,and the problem of antibiotic resistance of pathogenic bacteria has become increasingly serious.This has prompted many researches to explore new antibacterial agents that are environmentally friendly,have strong antibacterial activity,and do not easily produce drug resistance.Nanotechnology has been proved to be an effective means to fight against pathogens.Zinc oxide nanoparticles have excellent antibacterial properties and are expected to be widely used as new metal ion antibacterial materials.Compared with traditional physical and chemical methods,the biological method of zinc oxide nanoparticles has the advantages of simple operation,high safety,and less environmental pollution.It has become a new trend in the development of nano synthesis technology.In this paper,the biosynthesis methods and synthesis mechanism of zinc oxide nanoparticles using plant,algae and microorganism extracts are first summarised.Then,the antibacterial mechanism and antibacterial applications of zinc oxide nanoparticles in the pharmaceutical industry,textile industry,food industry,agriculture and other related fields are discussed.Finally,the related research and application prospects of innovative multi-metal composite nanoparticles containing zinc oxide are further discussed,providing new ideas for the development of zinc oxide nanotechnology.

关 键 词：氧化锌纳米颗粒 生物合成 抗菌机制 抑菌应用 多金属纳米材料 

分 类 号：TQ132.41[化学工程—无机化工] TB383.1[一般工业技术—材料科学与工程]