骨尤文肉瘤的影像学表现分析及临床随访  

Imaging analysis and clinical follow-up of Ewing sarcoma of bone

作　　者：丁升 陈亭亭[1] 王冬梅[1] 常莹[1] 杨献峰[1] Ding Sheng;Chen Tingting;Wang Dongmei;Chang Ying;Yang Xianfeng(Department of Medical Imaging,Drum Tower Hospital Affiliated to Nanjing University School of Medicine,Nanjing 210008,China)

机构地区：[1]南京大学医学院附属鼓楼医院医学影像科,南京210008

出　　处：《中国医师进修杂志》2023年第4期293-296,共4页Chinese Journal of Postgraduates of Medicine

摘　　要：目的分析归纳尤文肉瘤的影像学特征及临床随访结果。方法回顾性分析2010年5月至2021年10月在南京大学医学院附属鼓楼医院治疗的、经病理证实的23例骨尤文肉瘤患者的影像学资料,并进行临床随访。结果23例骨尤文肉瘤患者,有18例取得随访结果,5例失访;18例中死亡6例,12例存活,死亡原因主要为肺部转移;病灶共27处,发病部位以股骨干最为常见;各病灶影像均可见骨质结构破坏及软组织肿块影,25处病灶(92.59%,25/27)可见骨膜反应,不同骨类型之间骨质破坏和骨膜反应征象存在一定差异。结论骨尤文肉瘤影像主要表现为多种类型的骨质破坏、软组织肿块及骨膜反应;骨尤文肉瘤主要以骨髓转移及肺转移为主,其中肺转移为死亡的主要原因。Objective To analyze and summarize the imaging characteristics and clinical follow-up results of Ewing sarcoma of bone.Methods The imaging data of 23 patients with Ewing sarcoma confirmed by pathology who treatment in Drum Tower Hospital Affiliated to Nanjing University School of Medicine from May 2010 to October 2021 were retrospectively analyzed,and clinical follow-up was performed.Results Of the 23 patients with Ewing sarcoma of the bone in this group,a total of 18 patients had follow-up results and 5 cases were lost to follow-up.Of the 18 cases,6 cases died and 12 cases survived.The main cause of death was lung metastasis.There were 27 lesions in total,femoral diaphysis was the most common site of the disease;bone structure destruction and soft tissue mass shadows could be seen in the images of each lesion.Periosteal reaction could be seen in most of the lesions(92.59%,25/27).There were certain differences in signs of bone destruction and periosteal reaction between different bone types.Conclusions The imaging of Ewing sarcoma of bone mainly manifests various types of bone destruction,soft tissue masses and periosteal reactions.Ewing sarcoma of bone is mainly bone marrow metastasis and lung metastasis,and lung metastasis is the main cause of death.

关 键 词：骨肉瘤 随访研究 影像诊断 

分 类 号：R738.1[医药卫生—肿瘤]