Type 2 Diabetes and Hyperlipidemia Caused by AKT2 Gene Combined with PLIN1 Gene Mutation:A Case Report  

作　　者：LIU Jing LI Sheng Bing LUO Xie YUAN Lei LAI Ye Rui ZHANG Li Li 

机构地区：[1]Department of Endocrinology,the Second Affiliated Hospital,Chongqing Medical University,Chongqing 400010,China

出　　处：《Biomedical and Environmental Sciences》2023年第4期371-375,共5页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China[Grants 81300702 to L.L.Z.];the Natural Scienceof Chongqing CSTC[cstc2018jcyjAXO210 to L.L.Z.]。

摘　　要：Type 2 diabetes(T2DM)is a common metabolic disorder associated with environmental and genetic factors characterized by both insulin resistance and relative insufficiency of insulin secretion.T2DM has a high genetic predisposition.It is reported that 40% of first-degree relatives of patients with T2DM may develop diabetes;however,the incidence rate is only 6% in the general population[1].

关 键 词：T2DM AKT2 INSUFFICIENCY 

分 类 号：R589.2[医药卫生—内分泌] R587.2[医药卫生—内科学]