儿童神经母细胞瘤继发急性髓系白血病  

Secondary acute myeloid leukemia in children with neuroblastoma

作　　者：杜家曦 管雯斌[2] 马娟[3] 袁晓军[1] Du Jiaxi;Guan Wenbin;Ma Juan;Yuan Xiaojun

机构地区：[1]上海交通大学医学院附属新华医院儿血液/肿瘤科,上海200092 [2]上海交通大学医学院附属新华医院病理科,上海200092 [3]上海交通大学医学院附属新华医院检验科,上海200092

出　　处：《中华转移性肿瘤杂志》2023年第1期60-63,共4页Chinese Journal of Metastatic Cancer

摘　　要：神经母细胞瘤是儿童时期最常见的颅外实体肿瘤,但神经母细胞瘤患儿继发急性髓系白血病鲜有报道,其发生机制尚不明确且预后较差。本文报道了2例儿童神经母细胞瘤继发急性髓系白血病病例,分析可能导致其发生的危险因素,以期提高临床医生的认识,做到早期发现和干预,改善预后。Neuroblastoma is the most common extracranial solid tumor in childhood,but secondary acute myeloid leukemia in children with neuroblastoma is rarely reported,its occurrence mechanism is still unclear,and the prognosis is poor.In this study,two cases of secondary acute myeloid leukemia in children with neuroblastoma were reported.The possible risk factors were analyzed to enhance the understanding of clinicians,achieve early detection and intervention,and improve the prognosis.

关 键 词：神经母细胞瘤 继发性恶性肿瘤 急性髓系白血病 儿童 

分 类 号：R739.4[医药卫生—肿瘤] R733.71[医药卫生—临床医学]