功能等级引导骨再生膜的研究进展  

Research progress on functionally graded membranes for guided bone regeneration

作　　者：徐彦雪 付丽[1] Xu Yanxue;Fu Li(Dept.of Implantology,Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医院种植科,长春130021

出　　处：《国际口腔医学杂志》2023年第3期353-358,共6页International Journal of Stomatology

基　　金：吉林省财政厅科技项目(JCSZ2019378-7);吉林省卫生健康技术创新项目(2019J023);吉林省科技厅自然科学基金(20200201592JC)。

摘　　要：引导骨再生(GBR)是一种利用屏障膜实现骨组织再生的治疗方法。GBR膜的应用作为GBR术的关键,可以封闭骨缺损区,阻止非成骨细胞长入,为骨组织的再生创造一个良好的环境。然而,目前市面上的GBR膜往往缺乏骨诱导潜力和抗菌活性。为了实现屏障膜的多种功能需求,许多学者致力于研究具有梯度空间结构和功能的复合膜。本文将回顾功能等级GBR膜的研究进展并对其未来发展方向进行展望,为GBR膜的进一步研究提供思路。Guided bone regeneration(GBR)is a therapeutic modality to achieve bone tissue regeneration by using barrier membranes.As the key part of GBR,barrier membranes can seal the bone defect area,prevent non-osteogenic cell infiltration,and provide a benign environment for bone tissue regeneration.However,the effect of GBR membranes on the market is compromised by their limited bone regenerative potential and deficient antibacterial activity.To achieve the various functional requirements of barrier membranes,many studies have proposed a novel membrane composed of multiple layers with different compositions and structures.This article reviews the research progress on functionally graded membranes and discussed its development directions to provide reference for further research on GBR membranes.

关 键 词：功能等级膜 引导骨组织再生 骨缺损 

分 类 号：R783.1[医药卫生—口腔医学]