白光内镜、放大内镜及放大内镜联合窄带成像技术对早期胃癌的诊疗价值  

Value of white light endoscopy,magnification endoscopy and magnification endoscopy combined with narrow-band imaging in the diagnosis and treatment of early gastric cancer

作　　者：刘坤 徐菁 马竹芳 LIU Kun;XU Jing;MA Zhu-fang(Department of Gastroenterology,3201 Hospitall,Hanzhong Shaanxi 723000,China)

机构地区：[1]三二〇一医院消化内科,陕西汉中723000

出　　处：《临床和实验医学杂志》2023年第5期481-484,共4页Journal of Clinical and Experimental Medicine

基　　金：陕西省自然科学基金(编号:819MS129)。

摘　　要：目的探讨早期胃癌诊疗中白光内镜、放大内镜及放大内镜联合窄带成像技术的应用价值。方法回顾性选取2019年3月至2022年3月三二〇一医院疑似早期胃癌患者320例,统计3种检查方法的检测结果,分析320例早期胃癌患者的临床与病理特征,并分析早期胃癌患者微血管分型、微腺管分型与临床病理特征的相关性。结果放大内镜联合窄带成像技术诊断早期胃癌的灵敏性(80.00%)明显高于白光内镜(65.00%)和放大内镜(75.00%),差异有统计学意义(P<0.05),放大内镜检查的灵敏性明显高于白光内镜,差异有统计学意义(P<0.05),但三者的特异性、准确性、阳性预测值、阴性预测值之间的差异均无统计学意义(P>0.05)。分化程度为分化型患者的微血管分型FNP、ILL-1比率均明显高于未分化型患者,ILL-2、CSP比率均明显低于未分化型患者,差异均有统计学意义(P<0.05);镜下分型隆起型患者的微血管分型FNP、ILL-1比率均明显高于凹陷型或平坦型患者,ILL-2、CSP比率均明显低于凹陷型或平坦型患者,差异均有统计学意义(P<0.05)。未分化型患者的微腺管分型Ⅳ型、Ⅴ型比率均明显高于未分化型,Ⅵ型比率明显低于未分化型,差异均有统计学意义(P<0.05)。结论放大内镜联合窄带成像技术在早期胃癌诊疗中的应用价值明显高于白光内镜和放大内镜。Objective To investigate the value of magnifying endoscopy combined with narrowband imaging,magnifying endoscopy and white light endoscopy in the diagnosis and treatment of early gastric cancer.Methods A total of 320 patients with suspected early gastric cancer in Hanzhong 3201 Hospital of Shaanxi Province from March 2019 to March 2022 were retrospectively selected.The value of magnification endoscopy combined with narrowband imaging,magnification endoscopy and white light endoscopy in the diagnosis of early gastric cancer was statistically analyzed,and the clinical and pathological characteristics of patients with early gastric cancer were analyzed.The correlation between microvascular classification,microglandular classification and clinicopathological features in patients with early gastric cancer was analyzed.Results The sensitivity of magnifying endoscopy combined with narrowband imaging(80.00%)was higher than those of white light endoscopy(65.00%)and magnifying endoscopy(75.00%),and the sensitivity of magnifying endoscopy was higher than that of white light endoscopy,the differences were statistically significant(P<0.05),but there were no statistically significant differences in the specificity,accuracy,positive predictive value and negative predictive value of the three techniques(P>0.05).The ratios of FNP and ILL-1 in differentiated patients were higher than those in undifferentiated patients,and the ratios of ILL-2 and CSP were lower than those in undifferentiated patients,the differences were statistically significant(P<0.05).Microvascular FNP and ILL-1 ratios were higher in patients with protrusion type than those in patients with concave or flat type,and ILL-2 and CSP ratios were lower in patients with concave or flat type,the differences were statistically significant(P<0.05).The proportion of microglandular tube typeⅣandⅤin undifferentiated group was higher than that in undifferentiated group,and the proportion of microglandular tube typeⅥwas lower than that in undifferentiated group,the diffe

关 键 词：早期胃癌 白光内镜 放大内镜 窄带成像技术 临床病理特征 微血管分型 微腺管分型 

分 类 号：R735.2[医药卫生—肿瘤]