林奇综合征相关结直肠癌患者一级亲属癌症筛查行为的影响因素研究  

Predictive factors based on the health belief model on cancer screening behaviour in first degree relatives of patients with Lynch syndrome-associated colorectal cancer

作　　者：顾娇娇 贾书敏 巢花香 陈婷兰 吴晓丹 Jiaojiao Gu;Shumin Jia;Huaxiang Chao;Tinglan Chen;Xiaodan Wu(The Third Affiliated Hospital,Sun Yat-Sen University,Guangzhou,China;Li Ka Shing Faculty of Medicine,The University of Hong Kong,Hong Kong,China;State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-sen University Cancer Center,Guangzhou,China)

机构地区：[1]The Third Affiliated Hospital,Sun Yat-Sen University,Guangzhou,China [2]Li Ka Shing Faculty of Medicine,The University of Hong Kong,Hong Kong,China [3]State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-sen University Cancer Center,Guangzhou,China

出　　处：《International Journal of Nursing Sciences》2023年第2期251-257,共7页国际护理科学（英文）

摘　　要：目的 旨在调查林奇综合征相关结直肠癌患者一级亲属的大肠癌相关知识、健康信念和癌症筛查行为现状,并探讨基于健康信念模型的癌症筛查行为预测因素.方法 采用横断面调查法,选取2017年12月至2019年12月广州市1所三级甲等医院结直肠科96例林奇综合征相关结直肠癌患者的265名一级亲属.采用一般资料问卷、结直肠癌知识问卷(Colorectal Cancer Knowledge Questionnaire)、Champion's健康信念量表(Champion's Health Belief Model Scale,CHBMS)进行资料收集.采用描述性统计方法、组间比较和二元logistic回归进行资料分析.结果 林奇综合征相关结直肠癌患者一级亲属的大肠癌相关知识得分处于高、中、低水平的分别为160名(60.4%)、61名(23.0%)和44(16.6%);健康信念总均分为(121.36±13.02)分.61名(23.0%)研究对象接受过林奇综合征相关癌症筛查.Logistic回归分析结果显示,男性、年长、已婚、先证者为多原发癌症、较高的认知和健康信念水平是筛查行为的预测因素(P<0.05).结论 林奇综合征相关结直肠癌患者的一级亲属中关于癌症和癌症筛查的知识和健康信念亟待提高,而这两方面的知识和信念对于促进癌症筛查行为至关重要.干预措施应侧重于健康教育,并加强健康观念,以改善筛查行为.Objectives This study aimed to investigate colorectal cancer-related knowledge,health beliefs,and screening behaviour in first-degree relatives(FDRs)of patients with Lynch syndrome-associated colorectal cancer(CRC)and explore the predictive factors of screening behaviour based on a health belief model.Methods This cross-sectional study was conducted in the colorectal department of a Class A tertiary hospital in Guangzhou from December 2017 to December 2019.A total of 265 FDRs of 96 patients with Lynch syndrome-related CRC were selected.The study was conducted in the colorectal department of a tertiary cancer centre in Guangzhou.The demographic questionnaire,the simplified CRC knowledge questionnaire,and the Champion’s Health Belief Model Scale were used for evaluation.Data were analyzed using statistical description,between-group comparisons,and binary logistic regression.Results A total of 160(60.4%),61(23.0%),and 44(16.6%)of the participants had high,medium,and low levels of knowledge about CRC,respectively;the average overall score of health belief was 121.36±13.02.Sixty-one participants(23.0%)underwent Lynch syndrome-associated cancer screening.The predictive factors of screening behaviour included sex(male),age(older),married status(married),multiple primary cancers of the index patients,and high levels of knowledge and health beliefs(P<0.05).Conclusions The knowledge and health beliefs of cancer and cancer screening in FDRs of patients with Lynch syndrome-associated CRC should be improved.Both knowledge and beliefs are critical in promoting their cancer screening behaviour.Interventions should focus on health education and enhance health beliefs of the FDRs for better screening behaviour.

关 键 词：行为 亲属 健康信念 结直肠肿瘤 遗传性非息肉性 知识 

分 类 号：R735.34[医药卫生—肿瘤]