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作 者:王青 郁金凤 WANG Qing;YU Jinfeng(Department of Geriatrics,Nanjing Drum Towel Hospital,The Affiliated Hospital of Nanjing University Medical School,Jiangsu 210000,China)
机构地区:[1]南京大学医学院附属鼓楼医院老年科,210000 [2]南京大学医学院附属鼓楼医院输血科,210000
出 处:《医学研究杂志》2023年第4期98-101,共4页Journal of Medical Research
基 金:江苏省输血协会英科新创科研基金资助项目(JS2020007)。
摘 要:目的 分析青少年特发性脊柱侧弯后路矫形术中输注红细胞量的影响因素,为此类患者合理备血、科学用血提供参考。方法 收集2018年1~12月南京大学医学院附属鼓楼医院骨科收治的青少年特发性脊柱侧弯病例进行回顾性研究,根据术中红细胞输注量将患者分为术中输注红细胞>3U组和术中输注红细胞≤3U组,比较两组患者的临床资料,分析青少年特发性脊柱侧弯后路矫形术中输注红细胞量的影响因素。结果 296例行后路矫形术的青少年特发性脊柱侧弯患者中,术中输注红细胞>3U组119例,术中输注红细胞≤3U组177例。比较两组患者的相关临床指标,其中病程、住院时间、手术时长、术中出血量、术中输血量、术中输血浆量、冷沉淀输注率、血小板输注率的差异有统计学意义(P均<0.001)。多因素Logistic回归分析结果显示,病程和术中出血是青少年特发性脊柱侧弯后路矫形术中红细胞输注量的主要影响因素(P均<0.001)。结论 较长的病程和术中出血量的增加会增加青少年特发性脊柱侧弯后路矫形术中输注红细胞的风险。Objective To analyze the factors that affect the amount of red blood cells(RBC)transfusion during the posterior orthopaedic surgery for adolescent idiopathic scoliosis,so as to provide references for the reasonable preparation and scientific use of blood in such patients.Methods From June to Dec 2018,the patients with adolescent idiopathic scoliosis admitted to Department of Orthopedics,NanJing Drum Hospital,the Affiliated Hospital of Nanjing University Medical School were collected for retrospective study.According to the amount of intraoperative RBC transfusion,the patients were divided into two groups:the amount of intraoperative RBC transfusion>3U group and the amount of intraoperative RBC transfusion≤3U group.The relevant clinical indicators of the two groups were compared,and the influencing factors of the amount of intraoperative RBC transfusion during posterior orthopaedic surgery for adolescent idiopathic scoliosis were analyzed.Results Among the 296 adolescent patients with idiopathic scoliosis who underwent posterior orthopaedic surgery,119 cases were in the amount of intraoperative RBC transfusion>3U group and 177 cases in the amount of intraoperative RBC transfusion≤3U group.Relevant clinical indicators were compared between the two groups.There were statistically significant differences in the course of disease,length of hospital stay,operation duration,amount of intraoperative bleeding,amount of intraoperative blood transfusion,amount of intraoperative plasma transfusion,cerecipitation rate,platelet transfusion rate between the two groups(all P<0.001).Multivariate Logistic regression analysis showed that the course of disease and intraoperative bleeding were the main influencing factors of intraoperative RBC transfusion amount in patients with posterior orthopaedic surgery for adolescent idiopathic scoliosis(all P<0.001).Conclusion A longer course of disease and increased intraoperative bleeding amount increase the risk of RBC transfusion during posterior orthopaedic surgery for adolescent idio
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