抗甲状腺抗体阳性的视神经脊髓炎1例并文献复习  

One case of neuromyelitis optica with positive antithyroid antibody and literature review

作　　者：王子佳 王九雪 王天俊[2] Wang Zijia;Wang Jiuxue;Wang Tianjun(Graduate School of North China University of Science and Technology,Tangshan 063210,China;Department of Neurology,Hebei General Hospital,Shijiazhuang 050051,China)

机构地区：[1]华北理工大学研究生学院,河北唐山063210 [2]河北省人民医院神经内科,河北石家庄050051

出　　处：《临床荟萃》2023年第3期264-267,共4页Clinical Focus

摘　　要：目的 探讨抗甲状腺抗体与视神经脊髓炎的发病及预后相关性。方法 回顾性分析1例抗甲状腺抗体阳性的视神经脊髓炎患者的临床资料及抗体检测结果,并复习相关文献。结果 患者女,61岁,左侧肢体麻木10 d,加重3 d。脑脊液及血清检测结果提示脑脊液AQP4-IgG 1∶1阳性,血清AQP4-IgG 1∶100阳性。诊断为视神经脊髓炎。结论 视神经脊髓炎与甲状腺相关疾病常伴随出现,二者关系仍需更多研究才能得出明确的结论。Objective To investigate the correlation between antithyroid antibodies(ATAbs)and neuromyelitis optica(NMO).Methods The clinical data and antibody detection results of one NMO patient with positive ATAbs were retrospectively analyzed,and the related literatures were reviewed.Results The patient,61 years old female,left limb numbness for 10 days,aggravation for 3 days.The results of cerebrospinal fluid and serum indicated that aquaporin-4 immunoglobulin G(AQP4-IgG)-positive in cerebrospinal fluid and serum was 1∶1 and 1∶100,respectively.The diagnosis was NMO.Conclusion NMO and thyroid-related diseases are often associated,and more studies are needed to draw definite conclusions about their relationship.

关 键 词：视神经脊髓炎 甲状腺疾病 病例报告 

分 类 号：R744.52[医药卫生—神经病学与精神病学]