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作 者:Hongxue Xu Wei Zhang Mingfeng Wang
出 处:《Chinese Journal of Chemistry》2023年第4期458-468,共11页中国化学(英文版)
基 金:We acknowledge the financial support by the University Development Fund-Research Start-up Fund(UDF01001806)from the Chinese University of Hong Kong,Shenzhen.H.X.and W.Z.thank the financial support of Ph.D.Scholarship from the Chinese University of Hong Kong,Shenzhen.
摘 要:The discovery of fluorescent proteins has inspired a lot of interest to develop synthetic polymers with similar structures and functionalities.In this review article,we first give a brief introduction for the discovery,the structural characteristics and optical properties of fluorescent proteins,using green fluorescent protein(GFP)as an example.In the body part of article,we summarize recent advances in molecular design,synthesis and processing of bioinspired fluorescent polymers with unique optical properties such as high fluorescence quantum yield and robust photostability.Several major approaches highlighted here include the recombination of organic chromophores and proteins,and synthesis of the bioinspired polymers containing a single fluorophore in each polymer chain.The optical properties and applications of some representative bioinspired fluorescent polymers in bioimaging,sensing and imaging-guided therapy are also elucidated.
关 键 词:Green fluorescent protein FLUORESCENCE PROTEINS CHROMOPHORES POLYMERS
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