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作 者:Mitsuru Nagata
机构地区:[1]Department of Endoscopy,Shonan Fujisawa Tokushukai Hospital,Fujisawa 251-0041,Kanagawa,Japan
出 处:《World Journal of Gastrointestinal Endoscopy》2023年第4期259-264,共6页世界胃肠内镜杂志(英文版)(电子版)
摘 要:Different traction devices that can provide a visual field and attain appropriate tension at the dissection plane during endoscopic submucosal dissection(ESD)have been developed.Clip-with-line(CWL)is a classic traction device that can offer per-oral traction toward the direction where the line is drawn.A multicenter randomized controlled trial(CONNECT-E trial)comparing the conventional ESD and CWL-assisted ESD(CWL-ESD)for large esophageal tumors was conducted in Japan.This study showed that CWL-ESD was associated with a shorter procedure time(defined as the time from initiating submucosal injection to completing tumor removal)without increasing the risk of adverse events.Multivariate analysis revealed that whole-circumferential lesion and abdominal esophageal lesion were independent risk factors for technical difficulties,which were defined as a procedure time of>120 min,perforation,piecemeal resection,inadvertent incision(any accidental incision caused by the electrosurgical knife within the marked area),or handover to another operator.Therefore,techniques other than CWL should be considered for these lesions.Several studies have shown the usefulness of endoscopic submucosal tunnel dissection(ESTD)for such lesions.A randomized controlled trial conducted at five Chinese institutions showed that compared with the conventional ESD,ESTD had a significantly reduced median procedure time for lesions covering≥1/2 of the esophageal circumference.In addition,a propensity score matching analysis conducted at a single Chinese institution showed that compared with the conventional ESD,ESTD had a shorter mean resection time for lesions at the esophagogastric junction.With the appropriate use of CWL-ESD and ESTD,esophageal ESD can be performed more efficiently and safely.Moreover,the combination of these two methods may be effective.
关 键 词:Endoscopic submucosal dissection TRACTION Clip-with-line Endoscopic submucosal tunnel dissection
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