神经系统组织细胞肉瘤研究进展  

The research progress in the nervous system histiocytic sarcoma

作　　者：李颖[1] 孙伟平[1] LI Ying;SUN Weiping(Department of Neurol-ogy,Peking University First Hospital,8 Xishiku Street,Beijing 100034,China)

机构地区：[1]北京大学第一医院神经内科,北京100034

出　　处：《中国神经精神疾病杂志》2023年第3期189-192,共4页Chinese Journal of Nervous and Mental Diseases

摘　　要：组织细胞肉瘤(histiocytic sarcoma,HS)是一种来源于非朗格汉斯组织细胞的淋巴造血系统肿瘤,累及神经系统较罕见,导致临床医师对其认识不足。近年来,神经系统HS的个案报告逐渐增多。因此,本文通过系统回顾相关文献,对神经系统HS的临床表现、影像学特征、诊断、治疗及预后进行综述。综述发现神经系统HS的临床表现及影像学均缺乏特异性,诊断仍依赖于病理学检查。治疗上多采用手术或联合放化疗的方式,但最佳治疗方案仍不明确。该病预后极差,中位生存期6个月。Histiocytic sarcoma(HS)is an aggressive type of lymphohematopoietic tumor,which originates from non-Langerhans cells.Its presentation of the nervous system is extremely rare and as a result clinicians lack of knowledge of the disease.In recent years,the reports of nervous system HS have been dramatically increased.Therefore,this article reviews the clinical manifestations,imaging features,diagnosis,treatment and prognosis of the nervous system HS through systematic review of relevant literature.This review found that the clinical manifestations and imaging of the nervous system HS were lack of specificity,and the diagnosis still depends on pathological examination.The nervous system HS was usually treated by surgery,radiotherapy or chemotherapy,but the best treatment is still unclear.The prognosis of the nervous system HS is very poor with a median survival of 6 months.

关 键 词：组织细胞肉瘤 神经系统 临床表现 影像 诊断 治疗 预后 

分 类 号：R733[医药卫生—肿瘤]