咬合重建固定义齿修复术对牙周病伴牙列缺损患者颞下颌功能、脑血流速度及龈沟液IL-23、PGE_(2)的影响  

Effects of Occlusal Reconstruction and Fixed Tooth Restoration on Temporomandibular Function,Cerebral Blood Flow Velocity and Gingival Crevicular Fluid IL-23 and PGE_2 in Patients with Periodontal Disease with Dentition Defect

作　　者：蒋志勇[1] 于琼琼[1] JIANG Zhiyong;YU Qiongqiong(Department of Stomatology,the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第五附属医院口腔科,河南郑州450052

出　　处：《河南医学研究》2023年第8期1429-1434,共6页Henan Medical Research

摘　　要：目的 探讨咬合重建固定义齿修复术对牙周病(PD)伴牙列缺损患者颞下颌功能、脑血流速度及龈沟液白介素23(IL-23)、前列腺素E_(2)(PGE_(2))的影响。方法 选取2016年7月至2019年8月郑州大学第五附属医院收治的130例PD伴牙列缺损患者,根据治疗方案分为对照组和试验组,各65例。对照组接受垫式可摘局部义齿修复,试验组接受咬合重建固定义齿修复。治疗后观察6个月,统计两组修复效果、咀嚼功能、肌肉压痛指数、颞下颌关节紊乱指数、颞下颌关节功能障碍指数、龈沟液IL-23、PGE_(2)、舒张期末峰流速(Vd)、右侧大脑中动脉的收缩期峰流速(Vs)、平均峰流速值(Vm)、治疗满意度。结果 试验组总有效率高于对照组(P<0.05),咀嚼功能优良率高于对照组(P<0.05);修复6个月后试验组颞下颌关节功能障碍指数、肌肉压痛指数、颞下颌关节紊乱指数低于对照组,咀嚼状态下大脑中动脉Vs、Vd、Vm大于对照组(P<0.05),龈沟液IL-23水平低于对照组,PGE_(2)水平高于对照组(P<0.05),试验组语音功能、固位功能、咀嚼功能满意度高于对照组(P<0.05)。结论 咬合重建固定义齿修复术可改善PD伴牙列缺损患者咀嚼功能、颞下颌功能及脑血流速度,调节龈沟液IL-23、PGE_(2)水平,提高治疗满意度。Objective To investigate the effects of occlusal reconstruction and fixed tooth restoration on temporomandibular function,cerebral blood flow velocity and gingival crevicular fluid interleukin 23(IL-23)and prostaglandin E_(2)(PGE_(2))in patients with periodontal disease(PD)with dentition defect.Methods A total of 130 patients with PD with edentulism in the Fifth Affiliated Hospital of Zhengzhou University from July 2016 to August 2019 were selected,and 65 patients each were grouped according to different protocols.The control group was given a cushioned removable partial denture restoration and the test group was given an occlusal reconstruction fixed denture restoration.After 6 months of treatment,the restorative effect,masticatory function,muscle pressure pain index,temporomandibular joint disorder index,temporomandibular joint dysfunction index,gingival sulcus fluid IL-23,PGE_(2),end-diastolic peak flow velocity(Vd),systolic peak flow velocity(Vs)of the right middle cerebral artery,mean peak flow velocity value(Vm),and treatment satisfaction were measured in both groups.Results The total effective rate of the test group was higher than that of the control group(P<0.05),and the excellent rate of masticatory function was higher than that of the control group(P<0.05),the temporomandibular jiont dysfunction index,muscle tenderness index,and temporomandibular joint disorder index of the test group were lower than those of the control group after 6 months of repair,and the Vs,Vd and Vm of the middle cerebral artery in the masticatory state of the test group were greater than those of the control group(P<0.05).The level of IL-23 in the gingival sulcus fluid of the test group was lower than that of the control group after 6 months of repair,and the PGE_(2) level was higher than that in the control group(P<0.05).The satisfaction with speech function,retention function,and the chewing function in test group were higher than that in the control group(P<0.05).Conclusion The application of occlusal reconstruction and fixed

关 键 词：咬合重建固定义齿修复术 牙周病 牙列缺损 颞下颌功能 脑血流速度 白介素23 前列腺素E_(2) 

分 类 号：R783.4[医药卫生—口腔医学]