原发性肝癌患者CT表现及其与临床病理特征的关系  

CT Manifestations and Their Relationship with Clinicopathologic Features in Patients with Primary Hepatic Carcinoma

作　　者：陈辉[1] 黄文起[1] 郑吟诗[1] CHEN Hui;HUANG Wenqi;ZHENG Yinshi(Department of Radiology,the First People’s Hospital of Shangqiu,Shangqiu 476100,China)

机构地区：[1]商丘市第一人民医院放射科,河南商丘476100

出　　处：《河南医学研究》2023年第8期1471-1474,共4页Henan Medical Research

摘　　要：目的 分析原发性肝癌(PHC)CT表现与临床病理特征的关系。方法 对商丘市第一人民医院2018年1月至2022年10月收治的100例PHC患者的临床资料进行分析。患者均接受CT扫描,并经病理切片确诊。根据CT征象对PHC患者临床病理特征进行评价。分析患者病理分期、肝功能分级与CT征象表现的病灶大小、影像学分型、病灶位置、肿瘤形态、肿瘤边缘、动脉期强化、肿瘤包膜、肿瘤血供类型、门静脉癌栓的关系。采用Spearman相关系数分析临床病理分期、肝功能分级与病灶大小的关系。结果 病理分期Ⅲ~Ⅳ期患者病灶大于病理分期Ⅰ~Ⅱ期患者(P<0.05),病理分期Ⅲ~Ⅳ期患者肿瘤形态不规则、动脉期强化不均匀占比高于病理分期Ⅰ~Ⅱ期患者(P<0.05),两组强化程度比较,差异有统计学意义(P<0.05)。肝功能B级患者病灶大小大于A级患者(P<0.05),肝功能B级患者肿瘤形态不规则占比高于肝功能A级患者(P<0.05),肝动脉-门静脉供血占比低于肝功能A级患者(P<0.05),两组强化程度差异有统计学意义(P<0.05)。Spearman分析显示,临床病理分期、肝功能分级分别与病灶大小呈正相关(r=0.791、0.845,P<0.05)。结论 PHC患者的病理分期、肝功能分级与CT征象表现的肿瘤直径呈正相关。Objective To analysis the relationship between CT findings and clinicopathologic features of primary hepatic carcinoma(PHC).Methods The clinical data of 100 PHC patients admitted to Shangqiu First People’s Hospital from January 2018 to October 2022 was analyzed.All patients underwent CT scans and were confirmed by pathological sections.The clinical and pathological characteristics of PHC patients based on CT signs were evaluated.The relationship between pathological staging,liver function grading,and CT features of patients,including lesion size,imaging classification,lesion location,tumor morphology,tumor margin,arterial phase enhancement,tumor capsule,tumor blood supply type,and portal vein tumor thrombus were analyzed.The Spearman correlation coefficient was used to analyze the relationship between clinical pathological staging,liver function grading,and lesion size.Results The lesion size in patients with pathological stageⅢtoⅣwas larger than that in patients with pathological stageⅠtoⅡ(P<0.05),and the proportion of irregular tumor morphology and uneven arterial enhancement in patients with pathological stageⅢtoⅣwas higher than that in patients with pathological stageⅠtoⅡ(P<0.05).There was statistically difference in the degree of enhancement between the two groups(P<0.05).The lesion size of liver function grade B patients was larger than that of liver function grade A patients(P<0.05),the proportion of irregular tumor shape in liver function grade B patients was higher than that in liver function grade A patients(P<0.05),and the proportion of hepatic artery-portal vein blood supply was lower than that in liver function grade A patients(P<0.05).There was statistically difference in the degree of enhancement between the two groups(P<0.05).Spearman analysis showed that clinicopathologic stage and liver function grade were positively correlated with lesion size(r=0.791,0.845,P<0.05).Conclusion The pathological stage and liver function grade of the pathological features of PHC patients were posi

关 键 词：原发性肝癌 CT表现 病理分期 肝功能分级 肿瘤直径 

分 类 号：R735.7[医药卫生—肿瘤]