低频电刺激联合盐酸倍他司汀治疗椎-基底动脉供血不足伴颈动脉斑块患者的效果  

Effects of low-frequency electrical stimulation combined with Betahistine hydrochloride in treatment of patients with vertebral-basilar insufficiency and carotid plaques

作　　者：刘伟娜 LIU Weina(Department of Encephalopathy of Jiamusi Traditional Chinese Medicine Hospital,Jiamusi 154000 Heilongjiang,China)

机构地区：[1]佳木斯市中医医院脑病科,黑龙江佳木斯154000

出　　处：《中国民康医学》2023年第7期36-38,42,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察低频电刺激联合盐酸倍他司汀治疗椎-基底动脉供血不足(VBI)伴颈动脉斑块患者的效果。方法:选取2021年9月至2022年9月该院收治的100例VBI伴颈动脉斑块患者进行前瞻性研究,依照随机数字表法将其分为观察组和对照组各50例。对照组采用盐酸倍他司汀治疗,观察组在对照组基础上联合低频电刺激治疗,比较两组治疗前后动脉血流速度、血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、临床疗效和不良反应发生率。结果:治疗后,两组左、右椎动脉和基底动脉血流速度均大于治疗前,且观察组大于对照组,差异有统计学意义(P<0.05);治疗后,两组PT和APTT均短于治疗前,且观察组短于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率为98.00%(49/50),高于对照组的82.00%(41/50),差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:低频电刺激联合盐酸倍他司汀治疗VBI伴颈动脉斑块患者可提高治疗总有效率和动脉血流速度,缩短PT和APTT,效果优于单纯盐酸倍他司汀治疗。Objective:To observe effects of low-frequency electrical stimulation combined with Betahistine hydrochloride in treatment of patients with vertebral-basilar insufficiency(VBI)and carotid plaques.Methods:A prospective study was conducted on 100 patients with VBI and carotid plaques admitted to the hospital from September 2021 to September 2022.They were divided into observation group and control group according to the random number table method,50 patients in each group.The control group was treated with Betahistine hydrochloride,while the observation group was treated with low-frequency electrical stimulation on the basis of that of the control group.The arterial blood flow velocity,the plasma prothrombin time(PT),the activated partial thromboplastin time(APTT),the clinical efficacy,and incidence of adverse reactions were compared between the two groups before and after the treatment.Results:After the treatment,the blood flow velocities of left and right vertebral artery and basilar artery in the two groups were higher than those before the treatment,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the PT and APTT in the two groups were shorter than those before the treatment,those in the observation group were shorter than the control group,and the differences were statistically significant(P<0.05).The total effective rate of treatment in the observation group was 98.00%(49/50),which was higher than 82.00%(41/50)in the control group,and the difference was statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Low-frequency electrical stimulation combined with Betahistine hydrochloride in the treatment of the patients with VBI and carotid plaques can improve the total effective rate and the arterial blood flow velocity and shorten the PT and APTT levels.Moreover,it is superior to single Betahistine hydrochlo

关 键 词：低频电刺激 盐酸倍他司汀 椎-基底动脉供血不足 颈动脉斑块 动脉血流速度 凝血酶原 凝血活酶 

分 类 号：R743[医药卫生—神经病学与精神病学]