Diagnosis,treatment,and prevention of monkeypox in children:an experts'consensus statement  

作　　者：Rong-Meng Jiang Yue-Jie Zheng Lei Zhou Lu-Zhao Feng Lin Ma Bao-Ping Xu Hong-Mei Xu Wei Liu Zheng-De Xie Ji-Kui Deng Li-Juan Xiong Wan-Jun Luo Zhi-Sheng Liu Sai-Nan Shu Jian-She Wang Yi Jiang Yun-Xiao Shang Miao Liu Li-Wei Gao Zhuang Wei Guang-Hua Liu Gang Liu Wei Xiang Yu-Xia Cui Gen Lu Min Lu Xiao-Xia Lu Run-Ming Jin Yan Bai Le-Ping Ye Dong-Chi Zhao A-Dong Shen Xiang Ma Qing-Hua Lu Feng-Xia Xue Jian-Bo Shao Tian-You Wang Zheng-Yan Zhao Xing-Wang Li Yong-Hong Yang Kun-Ling Shen 

机构地区：[1]Diagnosis and Treatment Center of Infectious Diseases,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China [2]Department of Respiratory,Shenzhen Children’s Hospital,Shenzhen 518038,China [3]Branch for Emerging Infectious Disease,Public Health Emergency Center,Chinese Center for Disease Control and Prevention,Beijing 102206,China [4]School of Population Medicine&Public Health,Chinese Academy of Medical Science/Peking Union Medical College,Beijing 100730,China [5]Department of Dermatology,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health(Beijing),Beijing 100045,China [6]Department of Respiratory,Beijing Children’s Hospital,Capital Medical University,National Clinical Research Center for Respiratory Diseases,National Center for Children’s Health(Beijing),Beijing 100045,China [7]Department of Infectious Diseases,Children’s Hospital of Chongqing Medical University,Chongqing 400014,China [8]Tianjin Children’s Hospital,Children’s Hospital of Tianjin University,Tianjin 300134,China [9]Beijing Key Laboratory of Pediatric Respiratory Infection Diseases,Key Laboratory of Major Diseases in Children,Ministry of Education,National Clinical Research Center for Respiratory Diseases,Research Unit of Critical Infection in Children,Chinese Academy of Medical Sciences,2019RU016,Laboratory of Infection and Virology,Beijing Pediatric Research Institute,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health(Beijing),Beijing 100045,China [10]Department of Infectious Diseases,Shenzhen Children’s Hospital,Shenzhen 518038,China [11]Department of Infectious Diseases,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China [12]Ofce of Infection Management,Wuhan Children’s Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430016,China [13]Department of Neurology,Wuhan Children’s Hospital,Tongji Medical College,Huazhong University of Scien

出　　处：《World Journal of Pediatrics》2023年第3期231-242,共12页世界儿科杂志（英文版）

基　　金：National Natural Science Foundation of China(72174138);High-level Public health Talents Training Program of Beijing Municipal Health Commission(2022-2-002).

摘　　要：Monkeypox is a zoonotic disease.Since the first human monkeypox case was detected in 1970,it has been prevalent in some countries in central and western Africa.Since May 2022,monkeypox cases have been reported in more than 96 non-endemic countries and regions worldwide.As of September 14,2022,there have been more than 58,200 human monkeypox cases,and there is community transmission.The cessation of smallpox vaccination in 1980,which had some cross-protection with monkeypox,resulted in a general lack of immunity to monkeypox,which caused global concern and vigilance.As of Sep-tember 14,2022,there are four monkeypox cases in China,including three in Taiwan province and one in Hong Kong city.Previous foreign studies have shown that children are vulnerable to monkeypox and are also at high risk for severe disease or complications.In order to improve pediatricians'understanding of monkeypox and achieve early detection,early diagno-sis,early treatment,and early disposal,we have organized national authoritative experts in pediatric infection,respiratory,dermatology,critical care medicine,infectious diseases,and public health and others to formulate this expert consensus,on the basis of the latest"Clinical management and infection prevention and control for monkeypox"released by The World Health Organization,the"guidelines for diagnosis and treatment of monkeypox(version 2022)"issued by National Health Commission of the People's Republic of China and other relevant documents.During the development of this consensus,multidisciplinary experts have repeatedly demonstrated the etiology,epidemiology,transmission,clinical manifestations,laboratory examinations,diagnosis,differential diagnosis,treatment,discharge criteria,prevention,disposal process,and key points of prevention and control of suspected and confirmed cases.

关 键 词：CHILDREN CONSENSUS DIAGNOSIS MONKEYPOX PREVENTION TREATMENT 

分 类 号：R725.1[医药卫生—儿科]