Appraisal of gastric stump carcinoma and current state of affairs  

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作  者:Ankit Shukla Raja Kalayarasan Senthil Gnanasekaran Biju Pottakkat 

机构地区:[1]Department of Surgical Gastroenterology,Jawaharlal Institute of Postgraduate Medical Education and Research,Puducherry 605006,India

出  处:《World Journal of Clinical Cases》2023年第13期2864-2873,共10页世界临床病例杂志

摘  要:Gastric stump carcinoma,also known as remnant gastric carcinoma,is a malignancy arising in the remnant stomach following gastrectomy for a benign or malignant condition.Enterogastric reflux and preexisting risk factors in a patient with gastric cancer are the major contributors to the development of gastric stump carcinoma.The occurrence of gastric stump carcinoma is time-dependent and seen earlier in patients operated on for malignant rather than benign diseases.The tumor location is predominantly at the anastomotic site towards the stomach.However,it can occur anywhere in the remnant stomach.The pattern of lymph node involvement and the type of surgery required is distinctly different compared to primary gastric cancer.Gastric stump carcinoma is traditionally considered a malignancy with a dismal outcome.However,recent advances in diagnostic and therapeutic strategies have improved outcomes.Recent advances in molecular profiling of gastric stump carcinoma have identified distinct molecular subtypes,thereby providing novel therapeutic targets.Also,reports of gastric stump carcinoma following pancreatoduodenectomy and bariatric surgery highlight the need for more research to standardize the diagnosis,staging,and treatment of these tumors.The present review aims to provide an overview of gastric stump carcinoma highlighting the differences in clinicopathological profile and management compared to primary gastric carcinoma.

关 键 词:Gastric cancer GASTRITIS Carcinoma Endoscopic surveillance Gastric stump cancer Remnant gastric carcinoma 

分 类 号:R735.2[医药卫生—肿瘤]

 

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