甲基苯丙胺、海洛因依赖者的子宫、卵巢超声特征分析  

Analysis of Ultrasonic Characteristics of Uterus and Ovary in Methamphetamine and Heroin Addicts

作　　者：禹杭远 张利 张英霞 周艳 于春梅 YU Hangyuan;ZHANG Li;ZHANG Yingxia;ZHOU Yan;YU Chunmei(Department of Ultrasonography,Likang Compulsory Isolation Drug Rehabilitation Center of Beijing,Beijing 102600,China;Department of Gynaecology,Likang Compulsory Isolation Drug Rehabilitation Center of Beijing,Beijing 102600,China)

机构地区：[1]北京市利康教育矫治所超声科,北京102600 [2]北京市利康教育矫治所妇科,北京102600

出　　处：《中国药物滥用防治杂志》2023年第3期374-378,共5页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:分析甲基苯丙胺、海洛因依赖者子宫、卵巢超声特征,探究长期使用甲基苯丙胺、海洛因对女性生殖系统的损害,为临床诊疗提供解剖依据。方法:回顾性分析2019年1月—2022年7月因滥用甲基苯丙胺、海洛因在我院进行强制戒毒的女性,其中甲基苯丙胺依赖者79人作为甲基苯丙胺组,海洛因依赖者91人作为海洛因组,另外选取本单位健康职工60人作为对照组。所有入组对象均行超声检查,比较三组卵巢大小、子宫大小、卵巢血流参数。结果:甲基苯丙胺组子宫体、双侧卵巢积小于对照组,差异有统计学意义(P<0.05);海洛因组子宫、双侧卵巢体积小于对照组,差异有统计学意义(P<0.05);甲基苯丙胺组、海洛因组子宫、双侧卵巢体积比较,差异无统计学意义(P>0.05)。甲基苯丙胺组、海洛因组卵巢动脉血流峰值流速及舒张末期流速低于对照组,阻力指数高于对照组,差异有统计学意义(P<0.05);甲基苯丙胺组、海洛因组卵巢动脉血流峰值流速、舒张末期流速、阻力指数比较,差异无统计学意义(P>0.05)。结论:海洛因、甲基苯丙胺的长期滥用会导致女性卵巢、子宫形态及卵巢动脉发生明显改变,超声检查可以准确显示卵巢、子宫结构及血流情况,帮助临床进行精准治疗。Objective:To analyze the ultrasonic characteristics of uterus and ovary in methamphetamine and heroin addicts,and to explore the damage of long-term use of methamphetamine and heroin to female reproductive system,so as to provide anatomical basis for clinical diagnosis and treatment.Methods:From January 2019 to July 2022,women who abused methamphetamine and heroin in our hospital for compulsory detoxification were retrospectively analyzed.Among them,79 methamphetamine addicts were used as methamphetamine group,91 heroin addicts were used as heroin group,and 60 healthy workers were selected as control group.All the subjects were examined by ultrasonography,and the ovarian size,uterine size and ovarian blood flow parameters were compared among the three groups.Results:The volume of uterus and bilateral ovaries in the methamphetamine group was smaller than that in the control group,and the difference was statistically significant(P<0.05).The volume of uterus and bilateral ovaries in heroin group was smaller than that in control group(P<0.05).There was no significant difference in uterine and bilateral ovarian volume between methamphetamine group and heroin group(P>0.05).The peak velocity and end-diastolic velocity of ovarian artery blood flow in the methamphetamine group and the heroin group were lower than those in the control group,and the resistance index was higher than that in the control group(P<0.05).There was no significant difference in peak flow velocity,end diastolic velocity and resistance index of ovarian artery blood flow between methamphetamine group and heroin group(P>0.05).Conclusion:Long-term abuse of heroin and methamphetamine can lead to significant changes in female ovaries,uterine morphology and ovarian artery flowindices.Ultrasound examination has the advantage for planning the treatment accurately by detecting the structural and blood flow changes of ovary and uterus.

关 键 词：甲基苯丙胺 海洛因 超声检查 卵巢 子宫 

分 类 号：R749.64[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]