巴氏高温灭活法治疗四肢骨巨细胞瘤29例  

Pasteurized High-Temperature Inactivation on the Treatment of Giant Cell Tumor of Bone in Extremities 29 Cases

作　　者：蓝鋆 李若愚 周楠楠 方斌[1] 易春智[1] LAN Jun;LI Ruoyu;ZHOU Nannan;FANG Bin;YI Chunzhi(The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China)

机构地区：[1]广州中医药大学第一附属医院,广州510405

出　　处：《中国中医骨伤科杂志》2023年第4期56-59,共4页Chinese Journal of Traditional Medical Traumatology & Orthopedics

摘　　要：目的:探讨巴氏高温灭活法在四肢骨巨细胞瘤治疗中的应用及临床疗效。方法:收集2011年1月至2020年10月采用巴氏高温灭活联合刮除手术治疗四肢巨细胞瘤(GCT)29例患者病例资料。结果:随访时间为12~95个月,平均为56个月;28例患者肿瘤无进展;1例患者局部复发,再次行肿瘤扩大切除骨水泥填充钢板内固定重建;2例患者行克氏针内固定术后2个月因部分克氏针松动行取出术;其他患者均未出现感染、伤口愈合不良、骨折等并发症。国际骨肿瘤学会(MSTS)评分优14例,良11例,中4例,优良率为86.2%。结论:在四肢骨巨细胞瘤的手术治疗中联合巴氏高温灭活法可获得满意的肿瘤控制,且操作简单,经济有效,是一种可选的辅助灭活方式,值得在临床中推广应用。Objective:To evaluate the application and clinical efficacy of pasteurized high-temperature inactivation on the treatment of giant cell tumor of bone(GCTB)in the extremities.Methods:A total of 29 patients with giant cell tumor(GCT)limbs treated with pasteurized hyperthermia inactivation combined with curettage were collected from January 2011 to October 2020.Results:All patients were followed up 12 to 95 months with an average of 56 months.During the following-up,28 patients without tumor progression but 1 case had local recurrence with extensive tumor curettage and cement internal fixation reconstruction again,2 cases of patients underwent Kirschner wire removal 2 months after operation because of the partial Kirschner wire loosening.Other patients had no complications such as infection,poor wound healing or fracture.The musculoskeletal tumor society(MSTS)score was excellent in 14 cases,good in 11 cases,and fair in 4 cases,with an excellent and good rate of 86.2%.Conclusion:Satisfactory tumor control can be achieved on the surgical treatment of giant cell tumors of the limbs with pasteurized high-temperature inactivation.The operation is simple,cost-effective,and is an optional surgical method.It is worth promoting in clinical practice.

关 键 词：骨巨细胞瘤 巴氏高温灭活法 骨水泥 

分 类 号：R738.1[医药卫生—肿瘤]