2009—2019年四川省肝癌流行及生存情况分析  

Analysis of the prevalence and survival situation of liver cancer in Sichuan Province from 2009 to 2019

作　　者：邓颖[1] 王丹 成姝雯 张新 胥馨尹[1] 袁芝佩 董婷 DENG Ying;WANG Dan;CHENG Shuwen;ZHANG Xin;XU Xinyin;YUAN Zhipei;DONG Ting(Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China;Guang’an Center for Disease Control and Prevention,Guang’an 638000,Sichuan Province,China)

机构地区：[1]四川省疾病预防控制中心,成都610041 [2]广安市疾病预防控制中心,四川广安638000

出　　处：《预防医学情报杂志》2023年第4期359-363,共5页Journal of Preventive Medicine Information

摘　　要：目的描述四川省肝癌2009—2019年的发病死亡流行的变化情况,以及2016年以来的生存情况,为肝癌的防治提供科学依据。方法2009—2019年四川省肝癌的发病和死亡数据来源于四川省各市州肿瘤登记处提交到四川省肿瘤登记处,2009—2019年四川省肝癌患者生存数来源于“中国肿瘤登记平台”,用SAS 9.4软件计算分析肝癌发病、死亡和生存情况。用年度变化百分比(Annual Percentage Change,APC)描述发病率和死亡率,率的差异比较采用t检验,检验标准α=0.05。结果2009—2019年,四川省新发肝癌79593例,发病率为31.73/10万;死亡69796例,死亡率为27.82/10万;标化发病率(APC=-6.05,P<0.001)、粗死亡率(APC=-2.64,P=0.0018)、标化死亡率(APC=-6.01,P<0.001)均呈下降趋势。肝癌患者的1年、2年、3年、4年和5年的生存率分别是33.18%、18.72%、12.93%、9.83%和7.36%,5年生存率城市(7.97%)高于农村(6.98%)、女性(7.96%)高于男性(7.18%)。结论四川省肝癌的发病率处于全国中等水平,死亡率高于全国和其他省份,生存率低于全国和其他省份,应加强肝癌的筛查,早发现、早治疗以提高患者生存率。Objective To describe the change of the incidence and mortality of liver cancer in Sichuan Province from 2009 to 2019,to understand the survival situation since 2016,and to provide basis for the prevention and control of liver cancer.Methods The incidence and mortality data of liver cancer in Sichuan Province from 2009 to 2019 were submitted by cancer registries in various cities and prefectures to Sichuan Cancer Registry.The survival numbers of liver cancer patients in Sichuan Province from 2009 to 2019 were derived from the China Cancer Registration Platform.SAS 9.4 was used to calculate and analyze the incidence,mortality and survival situation of liver cancer.Annual percentage change(APC)was used to describe morbidity and mortality.The difference of rates was compared by t test,and the test level wasα=0.05.Results From 2009 to 2019,there were 79593 new cases of liver cancer in Sichuan Province,with an incidence rate of 31.73/105.There were 69 796 death cases,with a mortality rate of 27.82/105. The standardized incidence rate(APC=-6.05,P<0.001),crude mortality (APC=-2.64,P=0.001 8),and standardized mortality(APC=-6.01,P<0.001) all showed a downward trend. The 1-year,2-year,3-year,4-year and5- year survival rates of patients with liver cancer were 33.18%, 18.72%, 12.93%, 9.83% and7.36%,respectively. The 5-year survival rate in cities (7.97%) was higher than that in rural areas(6.98%),and the rate in women (7.96%) was higher than that in men (7.18%) . Conclusions Theincidence rate of liver cancer in Sichuan Province is at a medium level of the country. Themortality rate was higher than those of the country and other provinces,while the survival rate waslower than those of the country and other provinces. The screening of liver cancer,early detectionand early treatment should be strengthened to improve the survival rate of patients.

关 键 词：肝癌 发病率 死亡率 生存率 四川省 

分 类 号：R735.42[医药卫生—肿瘤] R181.3[医药卫生—临床医学]