2014—2018年四川省女性乳腺癌和宫颈癌流行特征及变化趋势分析  

Epidemiological characteristics and trends of female breast cancer and cervical cancer in Sichuan Province from 2014 to 2018

作　　者：王丹 成姝雯 董婷 曾晶[2] 祁冰洁 邓颖[2] WANG Dan;CHENG Shuwen;DONG Ting;ZENG Jing;QI Bingjie;DENG Ying(Guang’an Center for Disease Control and Prevention,Guang’an 638000,Sichuan Province,China;Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China)

机构地区：[1]广安市疾病预防控制中心,四川广安638000 [2]四川省疾病预防控制中心,成都610041

出　　处：《预防医学情报杂志》2023年第4期364-370,377,共8页Journal of Preventive Medicine Information

摘　　要：目的分析2014—2018年四川省肿瘤登记地区女性乳腺癌和宫颈癌发病和死亡的流行特征和变化趋势,为女性两癌防控提供科学依据。方法利用四川省肿瘤登记地区2014—2018年收集的女性乳腺癌和宫颈癌发病和死亡资料,计算女性乳腺癌和宫颈癌发病和死亡的粗率、中标发病(死亡)率、年龄别率,以及年度变化百分比(APC),以P<0.05为差异有统计学意义。结果2014—2018年四川省肿瘤登记地区女性乳腺癌和宫颈癌的平均发病率分别为23.95/10万、15.95/10万,中标发病率分别为16.80/10万、11.22/10万;平均死亡率分别为6.43/10万、5.51/10万,中标死亡率分别为4.19/10万、3.54/10万。女性乳腺癌发病和死亡率城市明显高于农村,宫颈癌城乡差别不大。5年期间女性乳腺癌发病和死亡水平相对稳定,趋势变化差异无统计学意(P均>0.05),宫颈癌发病率和死亡率呈上升趋势,APC分别为5.38%和3.83%(P均<0.05)。结论四川省女性乳腺癌发病和死亡水平相对稳定,而宫颈癌呈上升趋势,女性乳腺癌城市地区明显高于农村,宫颈癌城乡差别不大,中老年女性两癌威胁较大,应加强筛查、疫苗接种与健康教育。Objective To analyze the epidemiological characteristics and trends of the incidence and mortality of female breast cancer and cervical cancer in Sichuan cancer registration areas from 2014 to 2018,and to provide scientific basis for prevention and control of these two cancers in females.Methods Data on the incidence and death of female breast cancer and cervical cancer were collected in Sichuan cancer registration areas from 2014 to 2018.Crude incidence rate,mortality rate,age-standardized incidence/mortality rate by Chinese standard population(ASIR/ASMR),age specific rate,and annual percentage change(APC)of female breast cancer and cervical cancer were calculated.P<0.05 was considered to be statistically significant.Results The average incidence rates of female breast cancer and cervical cancer in Sichuan cancer registration areas from 2014 to 2018 were 23.95/105 and 15.95/105. The ASIRs were 16.80/105 and 11.22/105, respectively. Theaverage mortality rates were 6.43/105 and 5.51/105. And ASMRs were 4.19/105 and 3.54/105. Theincidence and mortality rates of female breast cancer in urban areas were significantly higher thanthose in rural areas, while the rates of cervical cancer between urban and rural areas had littledifference. The incidence and death of female breast cancer were relatively stable during the 5-yearperiod, and the trend change was not statistically significant (all P>0.05) . The incidence anddeath of cervical cancer increased, and the APC was 5.38% and 3.83% , respectively (all P<0.05) . Conclusions The incidence and death of female breast cancer were relatively stable inSichuan Province. While cervical cancer was on the rise. Female breast cancer was significantlyhigher in urban areas than in rural areas, and cervical cancer was not significantly differentbetween urban and rural areas. Middle-aged and elderly women are at greater risk of both cancers.Thus,screening,vaccination and health education should be strengthened.

关 键 词：乳腺癌 宫颈癌 发病率 死亡率 趋势分析 

分 类 号：R735.42[医药卫生—肿瘤] R181.3[医药卫生—临床医学]