肠造口患者抑郁症状发生率的Meta分析  

Incidence of depression in ostomy patients: a meta-analysis

作　　者：宫笑颜 吴晨曦[1] 高静[1] 柏丁兮[1] 王浩 游倩 何佳丽 GONG Xiao-yan(School of Nursing,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China)

机构地区：[1]成都中医药大学护理学院,四川成都611137

出　　处：《牡丹江医学院学报》2023年第2期95-101,共7页Journal of Mudanjiang Medical University

基　　金：四川省科技计划项目(2018SZ0376)。

摘　　要：目的系统评价肠造口患者抑郁症状发生率。方法系统检索PubMed、Embase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、万方数据库和维普数据库,收集关于肠造口患者抑郁症状发生率的文献,检索时限为建库至2022年3月。2名研究者分别筛选文献、提取资料并评价纳入文献的偏倚风险后,采用Stata 15.1软件进行Meta分析。结果共纳入16篇文献,包括1982例肠造口患者。Meta分析结果显示,肠造口患者抑郁症状发生率为45.0%[95%CI(36.9%~53.0%)]。亚组分析结果显示,性别为女性74.0%[95%CI(55.3%,92.7%)]、年龄<60岁44.6%[95%CI(33.9%,55.3%)]、病因为炎症性肠病49.5%[95%CI(40.7%,58.4%)]、造口时限为永久性造口41.5%[95%CI(22.3%,60.6%)]、抑郁程度为轻度56.8%[95%CI(51.1%,62.5%)]、抑郁诊断量表为SDS53.0%[95%CI(39.7%,66.4%)]的肠造口患者抑郁症状发生率更高。结论肠造口患者抑郁症状发生率较高,医务人员应重视其心理状况并适时给予心理干预,避免不良心理状态的发生和发展。Objective To systematically review the incidence of depression in patients with ostomy.Methods PubMed,Embase,The Cochrane Library,Web of Science,China Biomedical Literature Database,CNKI,Wanfang Database and VIP Database were systematically searched to collect literature on the incidence of depression in patients with ostomy from the establishment of each database to March 2022.Two investigators independently screened the literature,extracted data,and assessed the risk of bias of the included literature,and then used Stata 15.1 software to conduct Meta-analysis.Results A total of 16 articles were included,including 1982 patients with ostomy.Meta-analysis showed that the incidence of depression in patients with ostomy was 45.0%[95%CI(36.9%-53.0%)].The results of subgroup analysis showed that the incidence of depression was higher in:gender was 74.0%[95%CI(55.3%,92.7%)],age<60 years was 44.6%[95%CI(33.9%,55.3%)],cause of inflammatory bowel disease 49.5%[95%CI(40.7%,58.4%)]%)],the duration of ostomy was permanent ostomy 41.5%[95%CI(22.3%,60.6%)],the degree of depression was mild 56.8%[95%CI(51.1%,62.5%)],and the diagnostic tool was SDS 53.0%[95%CI(39.7%,66.4%)].Conclusion The incidence of depressive symptoms in patients with ostomy is high,so medical staff should pay attention to their psychological status and timely give psychological intervention to avoid the occurrence and development of adverse psychological state.

关 键 词：肠造口 抑郁 发生率 META分析 

分 类 号：R73[医药卫生—肿瘤]