肝硬化患者肠道菌群的改变与肌肉减少症的相关性研究进展  

Research progress on the correlation between changes in gut microbiota and sarcopenia in patients with cirrhosis

作　　者：贾少华 张健康[2] Jia Shaohua;Zhang Jiankang(Shanxi Medical University,Taiyuan 030001;Department of Gastroenterology,the First Affliated Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学,太原030001 [2]山西医科大学第一附属医院消化内科,太原030001

出　　处：《中华肝脏病杂志》2023年第3期332-336,共5页Chinese Journal of Hepatology

摘　　要：肌肉减少症是肝硬化常见的并发症之一。研究者发现,合并肌少症时肝硬化患者病死率提升。肌肉减少症的发生可能与其肠道环境改变所引起的炎症状态和代谢异常相关,但目前此类研究相对缺乏。现就肝硬化患者肠道环境的改变与肌少症的相关性及诊疗加以阐述,以期对该类患者的治疗提供借鉴和帮助。Sarcopenia is one of the common complications of cirrhosis.Studies have demonstrated that patients with cirrhosis combined with sarcopenia have a high mortality rate.The occurrence of sarcopenia may be associated with inflammatory states and metabolic abnormalities caused by changes in the gut microbiota environment,but such studies are currently relatively lacking.This article elaborates on the correlation between changes in the gut microbiota environment,as well as the diagnosis and treatment,in order to provide reference and assistance for the treatment of patients with cirrhosis and sarcopenia.

关 键 词：肌肉减少症 肝硬化 肠道菌群 菌群失调 

分 类 号：R575.2[医药卫生—消化系统]