河北省城市、农村地区成人甲状腺疾病流行病学调查分析  

Epidemiological investigation of adult thyroid diseases in urban and rural areas of Hebei Province

作　　者：郝志华 王绵[1] 郝慧瑶[1] 高明[1] 葛艳红[1] 朱秋霄 刘子渤 赵雪[1] 李杰[1] 王星 焦丽静 袁玲玲[1] 张力辉[1] Hao Zhihua;Wang Mian;Hao Huiyao;Gao Ming;Ge Yanhong;Zhu Qiuxiao;Liu Zibo;Zhao Xue;Li Jie;Wang Xing;Jiao Lijing;Yuan Lingling;Zhang Lihui(Department of Endocrinology,Second Hospital of Hebei Medial University,Shijiazhuang 050051,China)

机构地区：[1]河北医科大学第二医院内分泌科,石家庄050051

出　　处：《中华地方病学杂志》2023年第4期292-295,共4页Chinese Journal of Endemiology

基　　金：公益性行业科研专项(201402005);中华医学会临床医学科研专项(15010010589)。

摘　　要：目的了解河北省城市和农村地区成人甲状腺疾病患病及分布情况。方法采取多阶段分层整群抽样方法,分别选择河北省任丘市和鹿泉市李村镇作为城市、农村调查点,对当地18岁以上常住居民(≥5年)进行问卷调查、体格检查和甲状腺B超检查;并采集调查对象空腹静脉血进行血清甲状腺功能指标测定。结果共调查成人2650人,其中城市人口1393人、农村人口1257人;男性1357人、女性1293人。检出甲状腺疾病患者435例,检出率为16.42%;共包括7种甲状腺疾病,分别为亚临床甲状腺功能减退(60.92%,265/435),桥本甲状腺炎(34.02%,148/435),甲状腺功能减退(4.83%,21/435),单纯性甲状腺肿(3.22%,14/435),甲状腺功能亢进(2.53%,11/435),亚临床甲状腺功能亢进(2.53%,11/435),甲状腺癌(1.84%,8/435)。城市、农村人群甲状腺疾病检出率分别为21.18%(295/1393)、11.14%(140/1257),男、女性甲状腺疾病检出率分别为11.42%(155/1357)、21.66%(280/1293),18~<30、30~<40、40~<50、50~<60、≥60岁人群甲状腺疾病检出率分别为13.46%(91/676)、14.81%(81/547)、15.42%(89/577)、20.94%(85/406)、20.05%(89/444),不同地区、性别、年龄比较,差异均有统计学意义(χ^(2)=48.54、50.53、14.68,均P<0.05)。结论河北省城市和农村地区成人亚临床甲状腺功能减退检出率较高,其次是桥本甲状腺炎。应对城市女性人群甲状腺功能的筛查、评估和干预予以重视。Objective To study the prevalence and distribution of adult thyroid diseases in urban and rural areas of Hebei Province.Methods A multi-stage stratified cluster sampling method was used to select Renqiu City and Licun Town,Luquan City of Hebei Province as the urban and rural survey sites,respectively.Questionnaire survey,physical examination and thyroid B ultrasound examination were conducted on local permanent residents(≥5 years of residencies)over 18 years old.The fasting venous blood sample was collected to determine the serum thyroid function indicaters.Results A total of 2650 adults were surveyed,including 1393 urban residents and 1257 rural residents(1357 males and 1293 females).A total of 435 patients with thyroid diseases were diagnosed,the detection rate was 16.42%.There were seven thyroid diseases,including subclinical hypothyroidism(60.92%,265/435),Hashimoto's thyroiditis(34.02%,148/435),hypothyroidism(4.83%,21/435),simple goiter(3.22%,14/435),hyperthyroidism(2.53%,11/435),subclinical hyperthyroidism(2.53%,11/435),and thyroid cancer(1.84%,8/435).The detection rates of thyroid diseases in urban and rural areas were 21.18%(295/1393)and 11.14%(140/1257),respectively.The detection rates of thyroid diseases in males and females were 11.42%(155/1357)and 21.66%(280/1293),respectively.The detection rates of thyroid diseases in 18-<30,30-<40,40-<50,50-<60 and≥60 years old were 13.46%(91/676),14.81%(81/547),15.42%(89/577),20.94%(85/406)and 20.05%(89/444),respectively.There were statistically significant differences between different areas,gender and age groups(χ^(2)=48.54,50.53,14.68,P<0.05).Conclusions The detection rate of subclinical hypothyroidism in adults in urban and rural areas of Hebei Province is relatively high,followed by Hashimoto's thyroiditis.Attention should be paid to the screening,evaluation,and intervention of thyroid function among urban female populations.

关 键 词：甲状腺 城乡 流行病学 成人 

分 类 号：R581[医药卫生—内分泌] R181.3[医药卫生—内科学]