YKL-40蛋白在眼部疾病中的研究进展  

Research progress of YKL-40 protein in ocular diseases

作　　者：李彦 张瑶 许立帅[1,2] Li Yan;Zhang Yao;Xu Lishuai(Department of Ophthalmology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China;Medical School of Ophthalmology&Optometry,North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院眼科,南充637000 [2]川北医学院眼视光医学院,南充637000

出　　处：《中国医师杂志》2023年第4期634-637,共4页Journal of Chinese Physician

基　　金：南充市市校科技战略合作专项基金(22SXQT0168);川北医学院校级科研发展计划项目(CBY21-QA56)。

摘　　要：YKL-40蛋白又名壳多糖酶3样蛋白质1(CHI3L1),是一种在种族进化上高度保守的糖蛋白,属于"18-糖基水解酶"家族,也是一种分泌蛋白。大量研究表明YKL-40参与很多疾病的病理过程,其在眼部疾病的研究资料目前比较匮乏。本文主要针对国内外有关YKL-40在眼部疾病中的研究进展进行综述,以期为眼科临床进一步开展相关研究提供参考。YKL-40 protein,also called chitinase 3 like 1(CHI3L1),is a highly conserved secreted glycoprotein in racial evolution,belonging to the"18-glycosyl hydrolase"family.A large number of studies have shown that YKL-40 is involved in the pathological process of many diseases.There is little research information about YKL-40 in ocular diseases yet.This article mainly summarizes the research progress of YKL-40 in ocular diseases in the domestic and foreign literatures to provide reference for further clinical research.

关 键 词：眼疾病 壳多糖酶3样蛋白质1 YKL-40蛋白 

分 类 号：R730[医药卫生—肿瘤]