结直肠癌肝转移术前药物治疗的研究进展  

Research Advances in Preoperative Drug Therapy for Colorectal Cancer with Liver Metastasis

作　　者：林家威[1] 徐胜[1] Lin Jia-wei;Xu Sheng(Department of Colorectal and Anal Surgery,People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]广西壮族自治区人民医院结直肠肛门外科,广西南宁530021

出　　处：《中国社区医师》2023年第12期8-10,共3页Chinese Community Doctors

摘　　要：结直肠癌是临床中发病率较高的恶性肿瘤,且病死率高、预后差,对患者的生活质量及生命安全构成严重威胁。结直肠癌肝转移为目前临床疾病诊治的重点和难点,也是影响患者预后的重要因素。手术为目前临床治疗结直肠癌肝转移的常用手段,但是初始可切除率低,对于初始无法进行手术切除的结直肠癌肝转移患者,如何将其转化为可切除状态,是目前临床重点研究方向。该文对结直肠癌肝转移患者的术前药物治疗方法、疗效、目的等展开综述,为后续制定治疗方案提供参考。Colorectal cancer is a malignant tumor with a very high incidence rate,high fatality rate and poor prognosis in clinic,it may pose a serious threat to the quality of life and life safety of patients.Liver metastasis of colorectal cancer is the focus and difficulty of clinical disease diagnosis of treatment at present,and also an important factor affecting the prognosis of patients.At present,surgery is a common method for clinical treatment of colorectal cancer with liver metastasis,but the initial resectable rate is relatively low.For patients with colorectal cancer with liver metastasis who cannot receive initial resection,how to transform them into resectable status has become the focus of clinical research.This article mainly reviews the methods,efficacy and objectives of preoperative drug therapy for colorectal cancer patients with liver metastasis,so as to provide a reference for the formulation of follow-up treatment plans.

关 键 词：结直肠癌 肝转移 手术 药物 转化治疗 

分 类 号：R735.34[医药卫生—肿瘤]