多模式影像检查在Coats病诊断及随访中的应用  

Appliance of fundus multimodal imaging in the diagnosis and follow-up of Coats disease

作　　者：周子义 窦国睿 王雨生 Zhou Ziyi;Dou Guorui;Wang Yusheng(Department of Ophthalmology,Eye Institute of Chinese PLA,Xijing Hospital,Air Force Medical University,Xi’an 710032,China)

机构地区：[1]空军军医大学西京医院眼科全军眼科研究所,西安710032

出　　处：《国际眼科纵览》2023年第2期156-162,共7页International Review of Ophthalmology

基　　金：国家自然科学基金(81770936,81970814)。

摘　　要：Coats病以视网膜毛细血管扩张为明显特征。荧光素眼底血管造影是诊断Coats病视网膜血管扩张及渗漏的金标准。眼底照相及眼部B超也常用于Coats病的诊断及病情评估中,但因检查结果缺乏特异性,对Coats病诊断及随访帮助有限。OCT可直观呈现视网膜各层结构变化并明确病变层次,为Coats的临床诊断提供更丰富的信息。相干光断层扫描血管成像(optical coherence tomography angiography,OCTA)及超广角荧光素血管造影术(ultra-widefield fluorescein angiography,UWFA)可对Coats病的血管病变进行准确评估。多影像检查如超广角眼底照相(ultra-widefield fundus photograph,UWF)及炫彩照相等,对传统眼底照相技术进行了补充。UWF和UWFA结合OCT及OCTA检查能为Coats病的诊断及随访提供更全面的信息。Coats disease is characterized by retinal telangiectasia.Fundus fluorescein angiography(FFA)is the authentic standard for the diagnosis of retinal vasodilation and leakage in Coats disease.In addition,fundus photography and ocular B-ultrasound are also widely used in the diagnosis and evaluation of Coats disease.While considering the lack of specificity in the examination results,their assistance in the diagnosis and follow-up of Coats disease are limited.Optical coherence tomography(OCT)could display the structural changes of each layer of the retina and clarify the pathological tissues,providing plenty of information for the clinical diagnosis of Coats disease.Optical coherence tomography angiography(OCTA)and ultra-widefield fluorescein angiography(UWFA)could accurately evaluate the pathological condition of Coats disease.At the same time,ultra-widefield fundus photograph(UWF)and colored photography have supplemented more information with traditional fundus photography techniques.Therefore,the combination of UWF and UWFA with OCT and OCTA can provide more comprehensive information for the diagnosis of Coats disease,and provide a more comprehensive means of follow-up,evaluation and further understanding of the pathogenesis for the Coats disease.

关 键 词：眼底多模式影像 COATS病 相干光断层扫描 

分 类 号：R774.1[医药卫生—眼科]