2D腹腔镜手术治疗结肠癌肠梗阻的疗效及对患者炎症指标的影响分析  

Analysis of the efficacy of 2D laparoscopic surgery on intestinal obstruction due to colon cancer and its influence on inflammatory parameters

作　　者：吴波 WU Bo(Chaoyang Second Hospital,Chaoyang 122000,China)

机构地区：[1]朝阳市第二医院胃肠外科,122000

出　　处：《中国实用医药》2023年第9期49-51,共3页China Practical Medicine

摘　　要：目的评估2D腹腔镜手术治疗结肠癌肠梗阻的效果和对患者炎症指标的影响。方法30例结肠癌肠梗阻患者,根据手术的适应证不同分为观察组和对照组,各15例。观察组进行2D腹腔镜手术治疗,对照组进行开腹手术治疗。比较两组临床相关指标、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)水平。结果观察组术中出血量(106.2±25.8)ml少于对照组的(170.4±39.5)ml,切口长度(8.3±2.0)cm、术后排气时间(19.6±8.2)h、住院时间(6.2±1.5)d均短于对照组的(12.9±3.8)cm、(37.6±14.2)h、(9.5±2.0)d,差异均有统计学意义(P<0.05)。两组手术时间比较差异无统计学意义(P>0.05)。观察组TNF-α(39.6±9.8)pg/ml、IL-6(45.3±15.0)pg/ml、IL-10(189.3±35.8)pg/ml、CRP(39.71±13.85)mg/L均低于对照组的(50.2±11.4)pg/ml、(64.9±20.5)pg/ml、(281.6±60.3)pg/ml、(53.98±21.77)mg/L,差异有统计学意义(P<0.05)。结论对结肠癌肠梗阻进行2D腹腔镜手术治疗,其效果和开腹手术相同,但患者的功能修复更迅速,炎性症状缓解快。Objective To evaluate the effect of 2D laparoscopic surgery on intestinal obstruction due to colon cancer and its influence on inflammatory parameters.Methods A total of 30 patients with intestinal obstruction due to colon cancer were divided into observation group and control group according to different indications of surgery,with 15 cases in each group.The observation group received 2D laparoscopic surgery,and the control group received open surgery.The levels of clinically relevant indicators,tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-6(IL-6)and interleukin-10(IL-10)were compared between the two groups.Results The intraoperative blood loss of(106.2±25.8)ml in the observation group was less than that of(170.4±39.5)ml in the control group;the incision length of(8.3±2.0)cm in the observation group was shorter than that of(12.9±3.8)cm in the control group;the postoperative exhaust time of(19.6±8.2)h and hospitalization time of(6.2±1.5)d in the observation group were shorter than those of(37.6±14.2)h and(9.5±2.0)d in the control group;the differences were statistically significant(P<0.05).There was no statistically significant difference in operative time between the two groups(P>0.05).The observation group had TNF-αof(39.6±9.8)pg/ml,IL-6 of(45.3±15.0)pg/ml,IL-10 of(189.3±35.8)pg/ml,and CRP of(39.71±13.85)mg/L,which were lower than those of(50.2±11.4)pg/ml,(64.9±20.5)pg/ml,(281.6±60.3)pg/ml,and(53.98±21.77)mg/L in the control group,and the differences were statistically significant(P<0.05).Conclusion 2D laparoscopic surgery for intestinal obstruction due to colon cancer is as effective as open surgery,but patients have rapid functional repair and rapid remission of inflammatory symptoms.

关 键 词：结肠癌 2D腹腔镜手术 肠梗阻 炎症反应 

分 类 号：R735.3[医药卫生—肿瘤]