甲状腺乳头状癌行甲状腺全切除术前后生存质量分析  

Quality of Life Before and After Total Thyroidectomy for Papillary Thyroid Carcinoma

作　　者：郑晓宏 邱怀鹏 袁园 张少波[1] ZHENG Xiaohong;QIU Huaipeng;YUAN Yuan;ZHANG Shaobo(Department of Nail and Breast Surgery,People's Liberation Army Support Unit 910 Hospital,Quanzhou Fujian 362000,China;Department of Outpatient,People's Liberation Army Support Unit 910 Hospital,Quanzhou Fujian 362000,China)

机构地区：[1]中国人民解放军联勤保障部队第九一〇医院甲乳外科,福建泉州362000 [2]中国人民解放军联勤保障部队第九一〇医院门诊部,福建泉州362000

出　　处：《中国卫生标准管理》2023年第8期143-146,共4页China Health Standard Management

摘　　要：目的探讨甲状腺乳头状癌患者行甲状腺全切除术前后生存质量。方法回顾性分析中国人民解放军联勤保障部队第九一〇医院2020年3月—2022年2月收治的实施甲状腺全切除术治疗的甲状腺乳头状癌患者107例的临床资料,全部患者实施甲状腺全切除术治疗后,采用头颈部肿瘤生存质量量表对患者术后1、3、6个月的生活质量进行评价,随后将患者的性别、年龄、文化程度、家庭经济状况、是否进行了颈部淋巴结清扫术以及^(131)I治疗划分亚组,分析不同因素影响下患者分别在术后1、3、6个月的生活质量评分。结果该组患者术后1个月与术前相比身体状况、社会/家庭状况、情感状况、功能状况、头颈部附加条目评分以及量表总分均较低,但在术后3个月、术后6个月开始升高,在术后6个月上述评分与术前相比,差异无统计学意义(P>0.05)。不同家庭经济状况、文化程度、是否在术后接受了^(131)I治疗后患者的生活质量评分,差异无统计学意义(P>0.05)。女性与男性相比,年龄≥40岁与年龄<40岁,未实施颈部淋巴结清扫术的患者与实施颈部淋巴结清扫术的患者相比生存质量评分明显降低,差异有统计学意义(P<0.05)。结论对年龄较低、女性患者、实施了颈部淋巴结清扫术的甲状腺乳头状癌患者需要引起足够的重视,临床工作中需要增强术前与患者的沟通及交流,术中尽可能的缩小切口,术后给予可靠的药物治疗及其他方法处理等。Objective To explore and analyze the quality of life and its influencing factors in patients with papillary thyroid carcinoma before and after total thyroidectomy.Methods The clinical data of 107 patients with papillary thyroid carcinoma treated by total thyroidectomy in People's Liberation Army Support Unit 910 Hospital from March 2020 to February 2022 were retrospectively analyzed.After total thyroidectomy,the quality of life of the patients was evaluated by the head and neck cancer quality of life scale at 1 month,3 months and 6 months after operation.Then the patients were divided into subgroups according to gender,age,education level,family economic status,whether cervical lymph node dissection and ^(131)I treatment.The QOL scores of patients at 1 month,3 months and 6 months after surgery were analyzed under the influence of different factors.Results In this group,physical status,social/family status,emotional status,functional status,head and neck additional items score and scale total score were all lower one month after surgery than before surgery,but began to increase at 3 months and 6 months after surgery,and there was no statistical significance in the above scores at 6 months after surgery compared with before surgery(P>0.05).There was no significant difference in the life quality scores of patients with different family economic status,education level and whether they received 131I treatment after surgery(P>0.05).Compared with men,women aged≥40 years old and women aged<40 years old,the quality of life scores of patients who did not undergo cervical lymph node dissection were significantly lower than those who underwent cervical lymph node dissection,and the difference was statistically significant(P<0.05).Conclusion Adequate attention should be paid to younger,female patients and patients with thyroid papillary carcinoma who have undergone cervical lymph node dissection.In clinical work,preoperative communication and communication with patients should be enhanced,intraoperative incision should be r

关 键 词：甲状腺乳头状癌 甲状腺全切除术 生活质量 头颈部肿瘤生存质量量表 影响因素 颈部淋巴结清扫术 

分 类 号：R736[医药卫生—肿瘤]