迷走神经副神经节瘤十例诊断和治疗分析  

Diagnosis and treatment of 10 cases of vagal paraganglioma

作　　者：郭晓[1] 曹华[1] 张亚民[1] 王刘中[1] Guo Xiao;Cao Hua;Zhang Yamin;Wang Liuzhong(Department of Otorhinolaryngology Head and Neck Surgery,the First Afiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院咽喉头颈外科,郑州450052

出　　处：《中国实用医刊》2023年第4期5-8,共4页Chinese Journal of Practical Medicine

摘　　要：目的分析迷走神经副神经节瘤的临床特点, 探讨其诊断与治疗方法。方法回顾性分析郑州大学第一附属医院2010年1月至2021年7月收治的10例经手术及病理证实的迷走神经副神经节瘤患者的临床资料。结果术前各种影像学检查均未提示为迷走神经副神经节瘤, 其中3例提示副神经节瘤可能性。10例患者均经手术治疗, 其中8例为良性病变, 2例为恶性病变。10例患者经5~144个月随访(中位时间38个月)均生存, 肿瘤无复发和远处转移。术后所有患者均出现迷走神经损伤症状, 8例患者合并其他颅神经或交感神经损伤症状。结论迷走神经副神经节瘤临床少见, 易误诊。患者术后神经损伤常难以避免, 并发症较多, 因此需慎重选择合适的手术病例。Objective To analyze the clinical features,diagnosis and treatment of vagal paraganglioma.Methods A retrospective review was performed on clinical data of 10 patients with vagal paraganglioma confirmed by surgery and pathology in the First Affiliated Hospital of Zhengzhou University from January 2010 to July 2021.Results None of the 10 patients were identified as vagal paraganglioma by preoperative imaging examinations,among which 3 cases showed a high possibility of vagal paraganglioma.All the 10 patients were treated by surgery,of which 8 cases were benign tumor and 2 cases were malignant tumor.With a median follow-up time of 38 months(range:5-144 months),the 10 patients all survived without recurrence or distant metastasis.All patients had vagal palsy,moreover,8 patients were complicated by cranial nerve or sympathetic nerve deficits after operation.Conclusions Vagal paraganglioma are rare and liable to be misdiagnosed in clinical.Postoperative nerve injury is inevitable,and patients are prone to have various complications.Therefore,clinicians should select reasonable surgery cautiously.

关 键 词：副神经节瘤 迷走神经 头颈部肿瘤 

分 类 号：R739.4[医药卫生—肿瘤]