3D生物打印角膜组织的研究进展  

Research progress of 3D bioprinted corneas

作　　者：袁正 周春阳[1] Yuan Zheng;Zhou Chunyang(Chengdu University of Traditional Chinese Medicine,Chengdu,Sichaun,610075)

机构地区：[1]成都中医药大学,四川成都610075

出　　处：《中医眼耳鼻喉杂志》2023年第2期92-96,共5页Journal of Chinese Ophthalmology and Otorhinolaryngology

基　　金：四川省自然科学基金(编号:2022NSFSC0594)。

摘　　要：3D生物打印技术使用由活细胞、生物材料或活性生物分子组成的生物墨水,通过计算机辅助控制来制造具有生物活性的组织或器官替代物。在眼科领域,通过搭载不同类型的活性细胞可3D打印出具备生理功能的角膜组织。3D生物打印的个性化角膜植入物具备足够的机械强度和生物相容性,且含水率和透光率接近天然角膜组织,是一种很有前景的角膜替代方法,有望解决角膜供体稀缺的难题。3D bio-printing uses bio-inks composed of living cells,biomaterials or active biomolecules to create biologically active tissue or organ replacements through computer-aided control.In ophthalmology,corneal tissue with physiological functions can be 3D printed by carrying different types of functional cells.3D bio-printed personalized corneal implants have sufficient mechanical strength and biocompatibility,and the water content and transmittance of light are close to the natural corneal tissue,which is a promising alternative method for cornea and is expected to solve the problem of scarcity of corneal donors.

关 键 词：3D生物打印 组织工程角膜 水凝胶 活性细胞 

分 类 号：R77[医药卫生—眼科]