基于“肠道微生态”理论谈中医学从“肾”论治骨质疏松症的科学内涵  

On the scientific Connotation of TCM Treatment of Osteoporosis from "Kidney" Based on the Theory of "Intestinal Microecology"

作　　者：卢增鹏 于海洋 曹盼举 汪海燕 金宗英 蒋宜伟 马涛 张晓刚 Lu Zengpeng;Yu Haiyang;Cao Panju;Wang Haiyan;Jin Zongying;Jiang Yiwei;Ma Tao;Zhang Xiaogang(School of Clinical Medicine,Gansu University of Chinese Medicine,Lanzhou 730000,China;Affiliated Hospital of Gansu University of Chinese Medicine,Lanzhou 730000,China;Baoji Hospital of Chinese Medicine,Baoji 721000,China;Acupuncture and Moxibustion Massage College,Chengdu University of Chinese Medicine,Chengdu 610000,China;Jiuquan Hospital of Chinese Medicine,Jiuquan 735000,China)

机构地区：[1]甘肃中医药大学中医临床学院,兰州730000 [2]甘肃中医药大学附属医院,兰州730000 [3]宝鸡市中医医院,宝鸡721000 [4]成都中医药大学针灸推拿学院,成都610000 [5]酒泉市中医院,酒泉735000

出　　处：《世界科学技术-中医药现代化》2023年第1期395-400,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：甘肃省科学技术厅自然科学基金(21JR11RA161):基于炎症微环境调控骨与H型血管形成探讨生骨再造丸促进激素性股骨头坏死骨修复的机制,负责人:于海洋;国家中医药管理局(国中医药人教函[2022]75号):张晓刚全国名老中医药专家传承工作室建设项目,负责人:张晓刚。

摘　　要：骨质疏松症(osteoporosis,OP)是一种由骨代谢障碍所致慢性全身性骨病。肠道微生态系统是人体内最为复杂且非常重要的微生态系统。现代研究发现,肠道微生态系统可有效地调控骨代谢。中医学认为,肾主骨生髓,故而人体骨的疾病发生与中医“肾脏”功能的正常与否密切相关。在本文中,结合分子生物学的相关成果“肠道微生态”,论述中医肾经肠道微生态系统调节骨代谢,防治骨质疏松症,最终论述中医学从“肾”论治骨质疏松症的科学性,以期为中医药防治骨质疏松症提供新的研究途径。Osteoporosis(OP) is a chronic systemic bone disease caused by bone metabolism disorder.Intestinal microecosystem is the most complex and important microecosystem in human body.Modern studies have found that gut microecosystem can effectively regulate bone metabolism.According to Chinese medicine,kidney governs bone and generates marrow,so the occurrence of bone diseases is closely related to the normal function of kidney.In this paper,based on the research achievement of modern molecular biology "intestinal microecology",the author expounds the process of regulating bone metabolism and preventing osteoporosis by the intestinal microecology of kidney meridian of Chinese medicine,and finally discusses the scientificity of treating osteoporosis from "kidney" of Chinese medicine,so as to provide a new research way for the prevention and treatment of osteoporosis by Chinese medicine.

关 键 词：中医学 肾 肠道微生态 骨质疏松症 

分 类 号：R223.7[医药卫生—中医基础理论]