小肠细菌过度生长的检测及其在肠易激综合征诊治中的临床意义  

Detection of small intestinal bacterial overgrowth and its clinical significance in diagnosis and treatment of irritable bowel syndrome

作　　者：陈坚[1] 张会禄[1] 邱志兵[1] CHEN Jian;ZHANG Huilu;QIU Zhibing(Department of Gastroenterology,Huashan Hospital,Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华山医院消化内科,上海200040

出　　处：《上海医药》2023年第9期20-25,共6页Shanghai Medical & Pharmaceutical Journal

摘　　要：小肠细菌过度生长(small intestinal bacterial overgrowth,SIBO)是肠道菌群失调的一种特殊表现,可引起肠道局部炎症和免疫变化,进而引发多种消化系统症状,如腹泻、腹痛、腹胀和营养吸收障碍等。目前,SIBO在肠易激综合征发病中的作用已越来越受到关注。本文就SIBO的健康危害、SIBO检测方法和SIBO检测在肠易激综合征诊治中的临床意义作一综述。Small intestinal bacterial overgrowth(SIBO)is a specific form of intestinal microbiome disorder that can cause local inflammatory-immune response in the intestinal tract,resulting in a variety of digestive symptoms(such as diarrhea,abdominal pain,bloating and nutrition malabsorption).The role of SIBO in the pathogenesis of irritable bowel syndrome(IBS)is a highlight in the recent years.The present review will focus on the hazards of SIBO in human,various methods for the detection of SIBO,the clinical significance of SIBO in the diagnosis and treatment of IBS.

关 键 词：小肠细菌过度生长 肠易激综合征 呼气试验 

分 类 号：R574.5[医药卫生—消化系统] R574.4[医药卫生—内科学]