Implantable intracortical microelectrodes: reviewing the present with a focus on the future  

作　　者：Yang Wang Xinze Yang Xiwen Zhang Yijun Wang Weihua Pei 

机构地区：[1]State Key Laboratory of Integrated Optoelectronics,Institute of Semiconductors,Chinese Academy of Sciences,100083,Beijing,China [2]University of Chinese Academy of Sciences,100049,Beijing,China [3]Chinese Institute for Brain Research,102206,Beijing,China

出　　处：《Microsystems & Nanoengineering》2023年第1期37-53,共17页微系统与纳米工程（英文）

基　　金：supported by the National Key Technologies Research and Development Program of China (2017YFA0205903 and 2017YFA0701100);the National Natural Science Foundation of China (61634006 and 62071447);Shanghai Municipal Science and Technology Major Project (2021SHZDZX);and the Strategic Priority Research Program of the Chinese Academy of Sciences Pilot Project (XDB32030102,XDB32040203,and XDA16021305).

摘　　要：Implantable intracortical microelectrodes can record a neuron’s rapidly changing action potentials(spikes).In vivo neural activity recording methods often have either high temporal or spatial resolution,but not both.There is an increasing need to record more neurons over a longer duration in vivo.However,there remain many challenges to overcome before achieving long-term,stable,high-quality recordings and realizing comprehensive,accurate brain activity analysis.Based on the vision of an idealized implantable microelectrode device,the performance requirements for microelectrodes are divided into four aspects,including recording quality,recording stability,recording throughput,and multifunctionality,which are presented in order of importance.The challenges and current possible solutions for implantable microelectrodes are given from the perspective of each aspect.The current developments in microelectrode technology are analyzed and summarized.

关 键 词：RECORDING MICROELECTRODE OVERCOME 

分 类 号：TN91[电子电信—通信与信息系统]