罗汉果苷的功能及应用研究进展  

Research Progress on Function and Application of Mogroside

作　　者：魏炳琦 高小雨 刘延鑫[2] 徐华明[2] 王义翠 WEI Bingqi;GAO Xiaoyu;LIU Yanxin;XU Huaming;WANG Yicui(School of Pharmacy,Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China;School of Medicine,Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China)

机构地区：[1]河南中医药大学药学院,河南郑州450046 [2]河南中医药大学医学院,河南郑州450046

出　　处：《食品工业科技》2023年第11期434-441,共8页Science and Technology of Food Industry

基　　金：河南省中医药科学研究专项重点课题(2021ZY1055);普通课题(2021ZY2157,2022ZY2062);河南省自然科学基金(222300420484)。

摘　　要：罗汉果是目前我国常用的药食两用药材之一。现代药理学研究发现,罗汉果苷是罗汉果的主要活性成分之一,在预防保健和治疗疾病方面具有多种生物活性,罗汉果苷广泛应用在食品添加剂,抗衰老、运动营养补剂,抗炎剂,利咽喉产品、肠道菌群调节剂、新型药物载体等方面,但存在产品开发深度不够、纯度低和药理机制探究不深入等问题。本文检索了近几年来的相关文献,对罗汉果苷的调节血糖、降脂,抗氧化应激,抗疲劳,保肝、护肝及抗肝纤维化,抗炎,改善肺功能,保护神经,抗癌和促生殖等功能活性,以及罗汉果苷应用的新产品开发进行综述,以期为罗汉果苷的进一步的研究及相关产品的开发提供参考依据。Siraitiae Fructus is one of the commonly used medicinal and edible herbs in China.Modern pharmacological studies have found that mogroside is one of the important active components of Siraitiae Fructus,there are a variety of biological activities in disease prevention,health care and treatment.It has been widely applicated in food additives,anti-aging,sports nutrition supplements,anti-inflammatory agents,sore throat products,intestinal flora regulators,new drug carriers,etc..However,there are problems such as insufficient product development depth,low purity and in-depth exploration of pharmacological mechanisms.In this paper,the relevant literature in the past recent years is retrieved,and the biological activity of mogroside on blood sugar regulation,lipid lowering,anti-oxidative stress,anti-fatigue,liver protection,anti-hepatic fibrosis,anti-inflammatory,improving lung function,protecting nerves,anti-cancer and promoting reproduction development and other biological functions,as well as the development of new products for mogroside applications are reviewed,in order to provide a reference for further research on mogroside and the development of related products.

关 键 词：罗汉果 罗汉果苷 生物活性 产品 应用 

分 类 号：R284.1[医药卫生—中药学] S816.7[医药卫生—中医学]