The accumulation and toxicity of ZIF-8 nanoparticles in Corbicula fluminea  

作　　者：Cuilian Yang Jia Wen Zhuangzhuang Xue Xiyan Yin Yangfang Li Li Yuan 

机构地区：[1]College of Environmental Science and Engineering,Hunan University,Changsha 410082,China [2]Key Laboratory of Environmental Biology and Pollution Control(Hunan University),Ministry of Education,Changsha 410082,China

出　　处：《Journal of Environmental Sciences》2023年第5期91-101,共11页环境科学学报（英文版）

摘　　要：Metal-organic frameworks(MOFs)are promising new materials that have been intensively studied and possibly applied to various environmental remediation.However,little is known about the fate and risk of MOFs to living organisms in thewater environment.Here,the toxic effects of ZIF-8 nanoparticles(NPs)on benthic organisms were confirmed by sub-chronic toxicity experiments(7 and 14 days)using Corbicula fluminea as the model organism.With exposure doses ranging from 0 to 50 mg/L,ZIF-8 NPs induced oxidative stress behaviors similar to the hormesis effect in the tissues of C.fluminea.The oxidative stress induced by ZIF-8 NPs and the released Zn^(2+)was the crucial cause of the toxic effects.Besides,we also found that the ZIF-8 NPs and dissolved Zn^(2+)may result in different mechanisms of toxicity and accumulation depending on the dosages.The Zn^(2+)release rate of ZIF-8NPswas high at low dosages,leading to a higher proportion of Zn^(2+)taken up by C.fluminea than the particulate ZIF-8.Conversely,at high dosages,C.fluminea mainly ingested the ZIF-8 NPs and resulted in increased mortality.The results have important implications for understanding the fate and biological effects of ZIF-8 in natural aquatic environments.

关 键 词：ZIF-8 nanoparticles Dissolution behavior Benthic organism ECOTOXICITY 

分 类 号：X171.5[环境科学与工程—环境科学]