天津市部分城市社区老年人群轻度认知损害患病情况及影响因素分析  

Prevalence and influencing factors of mild cognitive impairment in elderly population in urban community of Tianjin

作　　者：孙艳[1] 范茹雪 陈慧丰[2] 尹洁 张楠[1] SUN Yan;FAN Ru-xue;CHEN Hui-feng;YIN Jie;ZHANG Nan(Department of Neurology,Tianjin Medical University General Hospital,Tianjin 300052,China;Department of Neurology,Tianjin Medical University General Hospital Airport Site,Tianjin 300308,China;Department of Traditional Chinese Medicine,Community Health Service Center of Wu Da Dao Street,Tianjin 300041,China)

机构地区：[1]天津医科大学总医院神经内科,300052 [2]天津医科大学总医院空港医院神经内科,300308 [3]天津市和平区五大道社区卫生服务中心中医科,300041

出　　处：《中国现代神经疾病杂志》2023年第4期303-309,共7页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：天津市卫生健康科技项目(项目编号:ZC20230)。

摘　　要：目的分析天津市部分城市社区老年人群轻度认知损害患病率及其影响因素。方法采用横断面调查和整群抽样方法招募2019年9月至2020年5月天津市和平区某街道4个社区行常规健康体检的3200例≥60岁老年人行认知功能评估及轻度认知损害危险因素筛查,最终纳入3194例,包括认知功能正常2831例、轻度认知损害340例、痴呆23例。采用单因素和多因素逐步法Logistic回归分析筛查轻度认知损害相关影响因素。结果共3194例受试者中轻度认知损害340例,患病率为10.64%。Logistic回归分析显示,70~79岁(OR=1.670,95%CI:1.275~2.187;P=0.000)、≥80岁(OR=3.168,95%CI:2.264~4.433;P=0.000)、体重指数<18.50 kg/m2(OR=3.602,95%CI:1.899~6.833;P=0.000)是轻度认知损害的危险因素;小学(OR=0.342,95%CI:0.148~0.790;P=0.012)、初中(OR=0.150,95%CI:0.066~0.337:P=0.000)、高中(OR=0.131,95%CI:0.058~0.294;P=0.000)、大学及以上(OR=0.068,95%CI:0.030~0.155;P=0.000)受教育程度以及有运动习惯(OR=0.786,95%CI:0.621~0.995;P=0.045)是认知功能正常的保护因素。结论天津市城市社区≥60岁老年人轻度认知损害患病率约为10.64%,且受年龄、体重、受教育程度和运动习惯的影响。Objective To investigate the prevalence of mild cognitive impairment(MCI)and related influencing factors among elderly population in urban community of Tianjin.Methods The crosssectional survey and cluster sampling method were used for prevalence survey.Total 3200 elderly people aged≥60 years old who underwent routine physical examination from four communities in Heping District of Tianjin from September 2019 to May 2020 were investigated by questionnaire survey and cognitive screening test,finally 3194 elderly people were recruited.Univariate and multivariate Logistic regression analyses were conducted to explore related influencing factors of MCI.ResultsTotal 340 subjects were diagnosed with MCI among 3194 elderly subjects,with a prevalence rate of 10.64%.Logistic regression analysis showed 70-79 years old(OR=1.670,95%CI:1.275-2.187;P=0.000),≥80 years old(OR=3.168,95%CI:2.264-4.433;P=0.000)and body mass index(BMI)18.50 kg/m2(OR=3.602,95%CI:1.899-6.833;P=0.000)were independent risk factors of MCI;and primary school(OR=0.342,95%CI:0.148-0.790;P=0.012),junior high school(OR=0.150,95%CI:0.066-0.337;P=0.000),senior high school(OR=0.131,95%CI:0.058-0.294;P=0.000),college and above(OR=0.068,95%CI:0.030-0.155;P=0.000)a Cnodn chluasviionng sexercise habits(OR=0.786,95%CI:0.621-0.995;P=0.045)were protective factors.The prevalence of MCI among elder people≥60 years old is 10.64%in urban community of Tianjin,and mainly influenced by age,body weight,educational level and exercise habits.

关 键 词：认知障碍 危险因素 LOGISTIC模型 天津 

分 类 号：R749.1[医药卫生—神经病学与精神病学]