碳纳米碎片-镍修饰电极电化学检测硝苯地平的研究  

Carbon Nano-fragments and Nickel Glass Carbon Electrode for the Electrochemical Detection of Nifedipine

作　　者：刘玲煜 张羽翔 周峰晨 马振[2] 姚川[1] 赵文博 吴宇昊 叶紫星 铁绍龙[2] 南俊民[2] LIU Lingyu;ZHANG Yuxiang;ZHOU Fengchen;MA Zhen;YAO Chuan;ZHAO Wenbo;WU Yuhao;YE Zixing;TIE Shaolong;NAN Junmin(Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province,Institute of Surface Micro and Nano Materials,College of Chemical and Materials Engineering,Xuchang University,Xuchang 461000,China;School of Chemistry,South China Normal University,Guangzhou 510006,China)

机构地区：[1]许昌学院化工与材料学院,许昌461000 [2]华南师范大学化学学院,广州510006

出　　处：《华南师范大学学报（自然科学版）》2023年第2期49-54,共6页Journal of South China Normal University(Natural Science Edition)

基　　金：河南省科技攻关计划项目(222102230083)。

摘　　要：通过溶胶-凝胶热还原法制备碳纳米碎片-镍(CNF-Ni)复合材料,用于玻碳电极的修饰,构建硝苯地平电化学传感器(CNF-Ni/GCE)。通过扫描电子显微镜、X射线衍射、红外光谱和电化学技术研究CNF-Ni/GCE电极的形貌和催化特性。结果表明:CNF-Ni/GCE修饰电极对硝苯地平具有良好的催化性能。在优化实验条件的基础上,利用差分脉冲伏安技术测定,硝苯地平浓度在4~160μmol/L范围内与其氧化峰电流呈良好的线性关系,检出限为2μmol/L。该方法可用于实际药品中硝苯地平的检测。Carbon nano-fragments-nickel(CNF-Ni)composites were synthesized by sol-gel thermal reduction method for the modification of glassy carbon electrodes and applied in the electrochemical sensor construction of nifedipine.The morphology and catalytic characteristic of CNF-Ni/GCE electrode were studied employing field emission scanning electron microscope,X-ray diffraction,fourier infrared spectrometer,and electrochemical technology.The results indicated that CNF-Ni/GCE electrode exhibited favourable electrocatalytic performance for nifedipine determination.Under the optimal conditions,using differential pulse voltammetry(DPV),the linear relationship between anode peak current and nifedipine concentrations was obtained from 4 to 160μmol/L,and the detection limits was 2μmol/L.The proposed method was employed to determine nifedipine in the actual drug detection.

关 键 词：碳纳米碎片-镍复合材料 溶胶凝胶-还原法 电化学检测 硝苯地平 

分 类 号：X522[环境科学与工程—环境工程]